Lőrincz Aba, Nudelman Hermann, Kormos Edina Ilona, Józsa Gergő
Department of Thermophysiology, Institute for Translational Medicine, Medical School, University of Pécs, 12 Szigeti Street, H7624 Pécs, Hungary.
Institute of Information and Electrical Technology, Faculty of Engineering and Information Technology, University of Pécs, Boszorkány Street 2, H7624 Pécs, Hungary.
J Clin Med. 2025 May 5;14(9):3200. doi: 10.3390/jcm14093200.
Syndactyly, the congenital fusion of digits, compromises hand function and esthetics. Although surgical separation is the standard treatment, the optimal timing of the intervention remains controversial. We prospectively analyzed 20 pediatric patients (86 operated fingers) undergoing syndactyly repair, comparing early (≤24 months) versus delayed (>24 months) surgery. Outcome measures included range of motion (ROM) at the metacarpophalangeal (MP), proximal interphalangeal (PIP), and distal interphalangeal (DIP) joints; complications (synostosis, nail deformities, finger length disparity, webbing); and patient-reported outcomes assessed by the Disabilities of the Arm, Shoulder, and Hand (DASH) and overall esthetic satisfaction scores. The median age at surgery was 31 months (IQR25/75: 24.75-36.5), with a median follow-up of 72 months (IQR25/75: 42.0-86.25). Notably, digits III (28.24%) and IV (29.41%) were predominantly affected. Delayed surgery resulted in significantly improved MP ROM (90.98° ± 8.44° vs. 73.13° ± 22.37°, = 0.004) and DIP ROM (76.28° ± 22.24° vs. 67.19° ± 22.78°, = 0.028), with a non-significant trend toward better PIP ROM (93.00° ± 25.18° vs. 77.37° ± 30.29°, = 0.075). Furthermore, the incidence of synostosis was markedly reduced in the delayed surgery group (6.0% vs. 38.9%, = 0.001). Despite superior joint function associated with delayed intervention, early surgery patients reported higher satisfaction with cosmetic results (3.00 vs. 2.80, = 0.028), while the DASH scores remained comparably low between groups (0.00 vs. 0.24, = 0.141). Finger length disparities and webbing were minimal. Our study challenges the conventional advocacy for early syndactyly repair, by demonstrating that delaying surgery beyond 24 months significantly enhances joint mobility and reduces the synostosis rate. However, the higher satisfaction observed as a result of early intervention suggests that surgical timing should be individualized for affected fingers, joints, and severities to balance the functional and cosmetic outcomes. Further studies are needed to define the optimal surgical timing and techniques for pediatric syndactyly.
并指,即手指的先天性融合,会损害手部功能和美观。尽管手术分离是标准治疗方法,但干预的最佳时机仍存在争议。我们前瞻性分析了20例接受并指修复的儿科患者(86根手术手指),比较早期(≤24个月)与延迟(>24个月)手术。结果指标包括掌指(MP)、近端指间(PIP)和远端指间(DIP)关节的活动范围(ROM);并发症(关节强直、指甲畸形、手指长度差异、蹼状瘢痕);以及通过手臂、肩部和手部功能障碍(DASH)评估的患者报告结局和总体美观满意度评分。手术时的中位年龄为31个月(IQR25/75:24.75 - 36.5),中位随访时间为72个月(IQR25/75:42.0 - 86.25)。值得注意的是,第三指(28.24%)和第四指(29.41%)受影响最为显著。延迟手术导致MP关节活动范围显著改善(90.98°±8.44°对73.13°±22.37°,P = 0.004)和DIP关节活动范围改善(76.28°±22.24°对67.19°±22.78°,P = 0.028),PIP关节活动范围有改善趋势但不显著(93.00°±25.18°对77.37°±30.29°,P = 0.075)。此外,延迟手术组关节强直的发生率显著降低(6.0%对38.9%,P = 0.001)。尽管延迟干预与更好的关节功能相关,但早期手术患者对美容效果的满意度更高(3.00对2.80,P = 0.028),而两组间DASH评分仍相当低(0.00对0.24,P = 0.141)。手指长度差异和蹼状瘢痕最小。我们的研究对早期并指修复的传统观点提出了挑战,表明手术延迟超过24个月可显著提高关节活动度并降低关节强直率。然而,早期干预带来的更高满意度表明,手术时机应根据受影响的手指、关节和严重程度进行个体化,以平衡功能和美容效果。需要进一步研究来确定儿科并指的最佳手术时机和技术。