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骨闪烁扫描及实验室检查提示一名髋部骨折中年男性患骨软化症

Bone Scintigraphy and Laboratory Clues to Osteomalacia in a Middle-Aged Man With Hip Fractures.

作者信息

Chuang Tzyy-Ling, Wang Yuh-Feng

机构信息

Department of Nuclear Medicine, Dalin Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Chiayi, Taiwan.

School of Medicine, Tzu Chi University, Hualien, Taiwan.

出版信息

Clin Nucl Med. 2025 Aug 1;50(8):751-755. doi: 10.1097/RLU.0000000000005935. Epub 2025 May 14.

DOI:10.1097/RLU.0000000000005935
PMID:40367228
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12208376/
Abstract

A 43-year-old man with a 1-year history of bilateral hip pain, worsened by standing and walking, presented with a limping gait. x-rays showed diffuse osteoporosis (osteoblastic-lytic), and a bone scan revealed symmetric uptake in the costochondral junctions (rosary beads), femoral neck, proximal tibia, and feet, with no visualization of the kidneys, suggesting a metabolic disorder or neoplasm. Computed tomography revealed osteolytic lesions in multiple bones. Suspecting metabolic bone disease or metastasis, laboratory tests were conducted. Magnetic resonance imaging confirmed bilateral femoral neck fractures. He underwent open reduction internal fixation for the hip fractures. The imaging and laboratory findings suggest osteomalacia.

摘要

一名43岁男性，双侧髋关节疼痛1年，站立和行走时加重，步态跛行。X线显示弥漫性骨质疏松（成骨细胞溶解性），骨扫描显示肋软骨关节（串珠）、股骨颈、胫骨近端和足部呈对称性摄取，肾脏无显影，提示代谢紊乱或肿瘤。计算机断层扫描显示多骨有溶骨性病变。怀疑为代谢性骨病或转移瘤，进行了实验室检查。磁共振成像证实双侧股骨颈骨折。他接受了髋关节骨折切开复位内固定术。影像学和实验室检查结果提示为骨软化症。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/513c/12208376/838d65819388/rlu-50-751-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/513c/12208376/482242a71980/rlu-50-751-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/513c/12208376/845354448af3/rlu-50-751-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/513c/12208376/901293c0798f/rlu-50-751-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/513c/12208376/838d65819388/rlu-50-751-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/513c/12208376/482242a71980/rlu-50-751-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/513c/12208376/845354448af3/rlu-50-751-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/513c/12208376/901293c0798f/rlu-50-751-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/513c/12208376/838d65819388/rlu-50-751-g004.jpg

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Clin Case Rep. 2023 Jul 4;11(7):e7644. doi: 10.1002/ccr3.7644. eCollection 2023 Jul.
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Osteomalacia Is Not a Single Disease.骨质软化症不是一种单一的疾病。
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