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医疗保险受益人的补贴药物覆盖范围丧失与死亡率

Loss of Subsidized Drug Coverage and Mortality among Medicare Beneficiaries.

作者信息

Roberts Eric T, Phelan Jessica, Schwartz Aaron L, Meara Ellen, Ruggiero Dominic, Estenson Lilly, Werner Rachel M, Figueroa José F

机构信息

Perelman School of Medicine and Leonard Davis Institute of Health Economics, University of Pennsylvania, Philadelphia.

Corporal Michael J. Crescenz Department of Veterans Affairs Medical Center, Philadelphia.

出版信息

N Engl J Med. 2025 May 29;392(20):2025-2034. doi: 10.1056/NEJMsa2414435. Epub 2025 May 14.

DOI:10.1056/NEJMsa2414435
PMID:40367373
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12119213/
Abstract

BACKGROUND

A total of 14 million Medicare beneficiaries receive the Low-Income Subsidy (LIS), which reduces cost sharing in Medicare Part D. Losing the LIS may impede medication access and affect mortality.

METHODS

Using 2015-2023 Medicare data, we identified dual-eligible Medicare-Medicaid beneficiaries, who automatically receive the LIS, and calculated annual rates of Medicaid and LIS loss. To examine the relationship between LIS loss and mortality, we leveraged a natural experiment arising from the relationship between the timing of Medicaid disenrollment and subsequent LIS loss. We compared beneficiaries disenrolling from Medicaid in January through June, who kept the LIS through December (6 to 11 additional months), with those disenrolling in July through December, who kept the LIS through the following December (12 to 17 additional months). Among persons disenrolling from Medicaid during 2015-2017, we examined cumulative mortality 7 to 17 months after disenrollment, when those with earlier disenrollment were more likely to lose the LIS.

RESULTS

The sample included 969,606 persons with early (January though June) Medicaid disenrollment and 920,158 with late (July though December) Medicaid disenrollment. Those with early Medicaid disenrollment averaged 13.6 cumulative months of the LIS in the 17 months after disenrollment, as compared with 15.3 months for those with late disenrollment. At 17 months after Medicaid disenrollment, cumulative mortality was higher among persons with early disenrollment (78.3 per 1000) than among those with late disenrollment (75.3 per 1000), a difference of 3.0 deaths per 1000 (95% confidence interval [CI], 2.1 to 3.9). Mortality differences between persons with early disenrollment and those with late disenrollment were amplified among those in the highest quintile of baseline Part D spending (5.6 deaths per 1000; 95% CI, 3.3 to 7.9) and users of medications for cardiovascular disease, chronic lung disease, or human immunodeficiency virus infection.

CONCLUSIONS

Loss of drug subsidies after Medicaid disenrollment was associated with higher mortality among low-income Medicare beneficiaries. (Funded by the National Institute on Aging and others.).

摘要

背景

共有1400万医疗保险受益人领取低收入补贴(LIS),该补贴可降低医疗保险D部分的费用分担。失去LIS可能会妨碍药物获取并影响死亡率。

方法

利用2015 - 2023年医疗保险数据,我们识别出自动领取LIS的双重资格医疗保险 - 医疗补助受益人,并计算医疗补助和LIS丧失的年发生率。为了研究LIS丧失与死亡率之间的关系,我们利用了因医疗补助退保时间与随后LIS丧失之间的关系而产生的一项自然实验。我们将1月至6月退保医疗补助且LIS保留到12月(额外保留6至11个月)的受益人,与7月至12月退保且LIS保留到次年12月(额外保留12至17个月)的受益人进行比较。在2015 - 2017年期间退保医疗补助的人群中,我们考察了退保后7至17个月的累积死亡率,此时较早退保的人更有可能失去LIS。

结果

样本包括969,606名早期(1月至6月)退保医疗补助的人和920,158名晚期(7月至12月)退保医疗补助的人。早期退保医疗补助的人在退保后的17个月中,LIS平均累积时长为13.6个月,而晚期退保的人为15.3个月。在医疗补助退保17个月后,早期退保者的累积死亡率(每1000人中有78.3人死亡)高于晚期退保者(每1000人中有75.3人死亡),每1000人相差3.0例死亡(95%置信区间[CI],2.1至3.9)。在基线D部分支出最高的五分之一人群(每1000人中有5.6例死亡;95%CI,3.3至7.9)以及心血管疾病、慢性肺病或人类免疫缺陷病毒感染药物使用者中,早期退保者与晚期退保者之间的死亡率差异更大。

结论

医疗补助退保后药物补贴的丧失与低收入医疗保险受益人较高死亡率相关。(由美国国立衰老研究所及其他机构资助。)

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9dde/12119213/b5306ce69b2d/nihms-2064729-f0004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9dde/12119213/c17e2587aeaf/nihms-2064729-f0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9dde/12119213/c4320e62c18a/nihms-2064729-f0002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9dde/12119213/ec777340eeb2/nihms-2064729-f0003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9dde/12119213/b5306ce69b2d/nihms-2064729-f0004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9dde/12119213/c17e2587aeaf/nihms-2064729-f0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9dde/12119213/c4320e62c18a/nihms-2064729-f0002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9dde/12119213/ec777340eeb2/nihms-2064729-f0003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9dde/12119213/b5306ce69b2d/nihms-2064729-f0004.jpg

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