Ghosh Sourav, Rothlin Carla V
Department of Neurology, Yale University School of Medicine, New Haven, CT 06520, USA; Department of Pharmacology, Yale University School of Medicine, New Haven, CT 06520, USA.
Department of Pharmacology, Yale University School of Medicine, New Haven, CT 06520, USA; Department of Immunobiology, Yale University School of Medicine, New Haven, CT 06520, USA.
Immunity. 2025 May 13;58(5):1179-1181. doi: 10.1016/j.immuni.2025.04.025.
The critical immunoregulatory function of the lung nerve- and airway-associated macrophages (NAMs) is increasingly becoming evident. In this issue of Immunity, Yeung et al. report that NAMs' response to type I interferon limits SARS-CoV-2 spread, inflammation, lung injury, and mortality.
肺神经和气道相关巨噬细胞(NAMs)的关键免疫调节功能日益明显。在本期《免疫》杂志中,杨等人报告称,NAMs对I型干扰素的反应限制了新冠病毒的传播、炎症、肺损伤和死亡率。