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法洛四联症肺动脉瓣保留修复术后残余右心室流出道梗阻的评估:一项超声心动图研究

Evaluation of Residual Right Ventricular Outflow Tract Obstruction After Pulmonary Valve-Sparing Repair of Tetralogy of Fallot: An Echocardiographic Study.

作者信息

Iacobelli Roberta, Tifi Priscilla, Perri Gianluigi, Ricci Zaccaria, Brancaccio Gianluca, Ragni Laura, d'Inzeo Victoria, Filippelli Sergio, Trezzi Matteo, Galletti Lorenzo

机构信息

Pediatric Cardiology, Clinical Area of Fetal and Cardiovascular Sciences, Bambino Gesù Children's Hospital, IRCCS, Rome, Italy.

Pediatric Cardiac Surgery, Clinical Area of Fetal and Cardiovascular Sciences, Bambino Gesù Children's Hospital, IRCCS, Rome, Italy.

出版信息

World J Pediatr Congenit Heart Surg. 2025 Nov;16(6):790-800. doi: 10.1177/21501351251336234. Epub 2025 May 14.

DOI:10.1177/21501351251336234
PMID:40368357
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12504781/
Abstract

BackgroundPulmonary valve-sparing repair (PVSR) of Tetralogy of Fallot (TOF) provides good results in selected patients. However, recurrent right ventricular outflow tract obstruction (RVOTO) can occur requiring surgical revision. We sought to evaluate the course of RVOTO after PVSR by serial echocardiographic (ECHO) assessment.MethodsA retrospective analysis was conducted in patients who underwent PVSR of TOF at our institution. Demographic, anatomical, surgical and 2D-ECHO data were collected. The cohort was divided into two groups: no reintervention group (group 1) and reintervention group (group 2).ResultsNinety-one patients were included in this study; 13 patients (14%) required reintervention. Right ventricular outflow tract ECHO peak gradient was significantly higher in group 2 at intraoperative transesophageal ECHO (iTEE) ( = .009), at hospital discharge ( = .021), at six months follow-up ( = .0001) and 12 to 36 months follow-up ( = .0001). A more prevalent subvalvular stenosis was found in group 2 at six months ( = .0011) and 12 to 36 months follow-up ( = .00069). An RVOT ECHO peak gradient of 30 mm Hg at iTEE ( = .025) and discharge ( = .011) was statistically associated with the need for reintervention.ConclusionsRight ventricular outflow tract peak gradient was significantly higher in group 2 than in group 1 at iTEE, discharge and follow-up, with an ECHO peak gradient of 30 mm Hg being predictive of reintervention At follow-up, residual RVOTO was prevalent at the subvalvular level in group 2. This information will be useful in clinical decision-making for TOF patients undergoing pulmonary valve sparing repair.

摘要

背景

法洛四联症(TOF)的保留肺动脉瓣修复术(PVSR)在特定患者中取得了良好效果。然而,可能会出现复发性右心室流出道梗阻(RVOTO),需要进行手术修正。我们试图通过连续超声心动图(ECHO)评估来评估PVSR术后RVOTO的病程。

方法

对在我们机构接受TOF的PVSR的患者进行回顾性分析。收集人口统计学、解剖学、手术和二维ECHO数据。该队列分为两组:无再次干预组(第1组)和再次干预组(第2组)。

结果

本研究纳入91例患者;13例患者(14%)需要再次干预。在术中经食管ECHO(iTEE)时(P = 0.009)、出院时(P = 0.021)、6个月随访时(P = 0.0001)以及12至36个月随访时(P = 0.0001),第2组的右心室流出道ECHO峰值梯度显著更高。在6个月时(P = 0.0011)以及12至36个月随访时(P = 0.00069),第2组发现更普遍的瓣下狭窄。iTEE时(P = 0.025)和出院时(P = 0.011)RVOT ECHO峰值梯度为30 mmHg与再次干预的需求在统计学上相关。

结论

在iTEE、出院时和随访时,第2组的右心室流出道峰值梯度显著高于第1组,ECHO峰值梯度为30 mmHg可预测再次干预。在随访时,第2组瓣下水平的残余RVOTO很普遍。这些信息将有助于接受保留肺动脉瓣修复术的TOF患者的临床决策。

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本文引用的文献

1
Commentary: The yin and yang in tetralogy of Fallot surgery.评论:法洛四联症手术中的阴阳学说
J Thorac Cardiovasc Surg. 2024 Jan;167(1):305-306. doi: 10.1016/j.jtcvs.2023.06.001. Epub 2023 Jun 7.
2
Long-term outcomes of tetralogy of Fallot repair: A 30-year experience with 960 patients.法洛四联症修复术的长期预后:960例患者的30年经验
J Thorac Cardiovasc Surg. 2024 Jan;167(1):289-302.e11. doi: 10.1016/j.jtcvs.2023.04.015. Epub 2023 May 9.
3
The American Association for Thoracic Surgery (AATS) 2022 Expert Consensus Document: Management of infants and neonates with tetralogy of Fallot.美国胸外科学会(AATS)2022 年专家共识文件:法洛四联症婴儿和新生儿的管理。
J Thorac Cardiovasc Surg. 2023 Jan;165(1):221-250. doi: 10.1016/j.jtcvs.2022.07.025. Epub 2022 Oct 26.
4
Preserving the pulmonary valve in Tetralogy of Fallot repair: Reconsidering the indication for valve-sparing.法洛四联症矫治术中保留肺动脉瓣:重新考虑瓣膜保留的适应证。
J Card Surg. 2022 Dec;37(12):5144-5152. doi: 10.1111/jocs.17156. Epub 2022 Nov 15.
5
Pulmonary valve preservation during tetralogy of Fallot repair: midterm functional outcomes and risk factors for pulmonary regurgitation.法洛四联症矫治术中肺动脉瓣的保留:中期功能结果和肺动脉瓣反流的危险因素。
Eur J Cardiothorac Surg. 2022 Jul 11;62(2). doi: 10.1093/ejcts/ezac365.
6
Applicability and Durability of Valve-Sparing Tetralogy of Fallot Repair.可适用性和耐久性的法洛四联症修复手术。
World J Pediatr Congenit Heart Surg. 2021 Sep;12(5):628-634. doi: 10.1177/21501351211031242.
7
Comparison of Long-term Outcomes of Valve-Sparing and Transannular Patch Procedures for Correction of Tetralogy of Fallot.保留瓣叶和跨瓣环补片在法洛四联症矫治术中的长期疗效比较。
JAMA Netw Open. 2021 Jul 1;4(7):e2118141. doi: 10.1001/jamanetworkopen.2021.18141.
8
The progression of an acceptable pulmonary stenosis immediately after total correction of tetralogy of Fallot.法洛四联症根治术后即刻出现可接受的肺动脉瓣狭窄进展。
Cardiol Young. 2020 Jun;30(6):774-778. doi: 10.1017/S1047951120000955. Epub 2020 May 4.
9
Pulmonary Valve-Sparing Techniques for Tetralogy of Fallot: A Systematic Approach for Maximizing Success and Minimizing Risk.
Semin Thorac Cardiovasc Surg Pediatr Card Surg Annu. 2020;23:24-28. doi: 10.1053/j.pcsu.2020.02.005.
10
Importance of pulmonary valve morphology for pulmonary valve preservation in tetralogy of Fallot surgery: comparison of the echocardiographic parameters.法洛四联症手术中肺动脉瓣形态对肺动脉瓣保留的重要性:超声心动图参数比较
Clin Exp Pediatr. 2020 May;63(5):189-194. doi: 10.3345/kjp.2019.01060. Epub 2019 Nov 8.