Nelson K E, Warren D, Tomasi A M, Raju T N, Vidyasagar D
Am J Dis Child. 1985 Sep;139(9):903-5. doi: 10.1001/archpedi.1985.02140110057029.
Two cases of neonatal listeriosis occurred in a hospital within a two-week period. Both infants were infected with the same organism, Listeria monocytogenes, type 1a, bacteriophage type 6 (lysotype 1652). Both infants were born in the same delivery room, 17 hours apart. The index patient became septic shortly after birth and died after 48 hours despite antibiotic therapy. The mother of the index patient was febrile and had chorioamnionitis. The second infant became ill with meningitis at 13 days of age. Neither infants nor mothers were attended by the same medical or nursing staff nor were they in the same labor or postpartum areas or nurseries. However, both infants were resuscitated in the same delivery room after birth by means of laryngoscope, suction catheter, and emergency resuscitation (Ambu) bag. Although it was hospital policy to clean and sterilize resuscitation equipment after use, the equipment had only been wiped with alcohol between patients in this instance, since sterile replacement equipment was not available during the early-morning hours when the index birth occurred. Therefore, we believe the contaminated resuscitation equipment was the source of infection in the second infant. This episode emphasizes the importance of appropriate disinfection of respiratory resuscitation equipment to prevent nosocomial infection due to L monocytogenes, an unusual but important pathogen in neonates.
在两周内，一家医院发生了两例新生儿李斯特菌病病例。两名婴儿均感染了同一菌株，即1a型单核细胞增生李斯特菌，噬菌体6型（溶菌型1652）。两名婴儿在同一产房出生，间隔17小时。首例患儿出生后不久即发生败血症，尽管接受了抗生素治疗，但48小时后仍死亡。首例患儿的母亲发热，患有绒毛膜羊膜炎。第二名婴儿在13日龄时患脑膜炎。无论是婴儿还是母亲，都没有由相同的医护人员照料，也不在相同的分娩区、产后区或托儿所。然而，两名婴儿出生后均在同一产房通过喉镜、吸痰导管和急救复苏（复苏）袋进行了复苏。尽管医院规定使用后对复苏设备进行清洁和消毒，但在本例中，设备仅在患者之间用酒精擦拭，因为在首例婴儿清晨出生时没有无菌替换设备。因此，我们认为受污染的复苏设备是第二名婴儿的感染源。这一事件强调了对呼吸复苏设备进行适当消毒以预防由单核细胞增生李斯特菌引起的医院感染的重要性，单核细胞增生李斯特菌是新生儿中一种不常见但重要的病原体。
