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起源于右心室流出道高位和肺动脉的室性心律失常的心电图特征

Electrocardiographic Characteristics of Ventricular Arrhythmias Originating From High Right Ventricular Outflow Tract and Pulmonary Artery.

作者信息

Kuo Ming-Jen, Lin Chin-Yu, Huang Jin-Long, Lin Yenn-Jiang, Hsieh Yu-Cheng, Chang Shih-Lin, Lo Li-Wei, Hu Yu-Feng, Chung Fa-Po, Li Cheng-Hung, Chang Ting-Yung, Kuo Ling, Wu Cheng-I, Liu Chih-Min, Liu Shin-Huei, Huang Yu-Shan, Chen Shih-Ann

机构信息

Cardiovascular Center, Taichung Veterans General Hospital, Taichung, Taiwan.

Institute of Clinical Medicine, National Yang-Ming Chiao-Tung University, Taipei, Taiwan.

出版信息

J Cardiovasc Electrophysiol. 2025 Jul;36(7):1590-1600. doi: 10.1111/jce.16714. Epub 2025 May 14.

Abstract

BACKGROUND

Ventricular arrhythmias (VAs) may originate from the right ventricular outflow tract (RVOT) below the pulmonary sinus cusps (PSCs) or from the pulmonary artery (PA) above the PSCs. However, the electrocardiographic (ECG) characteristics of these VAs are not well defined.

OBJECTIVE

This study aimed to investigate the ECG characteristics of VAs originating from the high RVOT and PA.

METHODS

Patients who underwent catheter ablation for VAs originating from the RVOT or PA were retrospectively reviewed. Patients with VAs exhibiting a left bundle branch block pattern and an inferior axis on ECG, who also underwent pulmonary artery angiography, were included. Three-dimensional electroanatomic mapping was performed for all patients. The origin of the VAs, either below the pulmonary sinus cusps (Group 1: high RVOT group) or above the pulmonary sinus cusps (Group 2: PA group), was confirmed via PA angiography.

RESULTS

Thirty-seven patients were in Group 1, and 36 were in Group 2. In Group 2, significantly shorter R wave peak times (RWPT) were measured in leads II, III, and aVF on surface ECG during VAs. The cutoff values for RWPT were 66, 66, and 69 ms, respectively, with high area under the curve values of 0.944, 0.944, and 0.913, respectively.

CONCLUSION

VAs originating from the PA exhibit shorter RWPT in leads II, III, and aVF on surface ECG, distinguishing them from VAs originating from the high RVOT. These findings can aid in preprocedural planning, facilitating the mapping and ablation of the supra-PSC region based on surface ECG characteristics.

摘要

背景

室性心律失常(VAs)可能起源于肺窦瓣(PSCs)下方的右心室流出道(RVOT)或PSCs上方的肺动脉(PA)。然而,这些室性心律失常的心电图(ECG)特征尚未明确。

目的

本研究旨在探讨起源于高位RVOT和PA的室性心律失常的心电图特征。

方法

回顾性分析接受导管消融治疗起源于RVOT或PA的室性心律失常的患者。纳入心电图表现为左束支传导阻滞图形且电轴向下,同时接受肺动脉造影的室性心律失常患者。所有患者均进行三维电解剖标测。通过肺动脉造影确定室性心律失常的起源,即肺窦瓣下方(第1组:高位RVOT组)或肺窦瓣上方(第2组:PA组)。

结果

第1组有37例患者,第2组有36例患者。在第2组中,室性心律失常发作时,体表心电图II、III和aVF导联的R波峰时间(RWPT)明显缩短。RWPT的截断值分别为66、66和69毫秒,曲线下面积值分别为0.944、0.944和0.913。

结论

起源于PA的室性心律失常在体表心电图II、III和aVF导联表现出较短的RWPT,这使其与起源于高位RVOT的室性心律失常相区别。这些发现有助于术前规划,基于体表心电图特征促进PSCs上方区域的标测和消融。

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