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肝内胆管导管内乳头状黏液性肿瘤:一例报告及文献复习

Intraductal papillary mucinous neoplasm of the intrahepatic bile duct: a case report and literature review.

作者信息

Zhang Ying, Jia Fan, Wang Kai-Ge

机构信息

Department of Pathology, Beijing ChaoYang Hospital, Capital Medical University Beijing 100020, China.

Department of Hepatopancreatobiliary Surgery, Beijing Chuiyangliu Hospital Affilicated to Tsinghua University Beijing 100020, China.

出版信息

Int J Clin Exp Pathol. 2025 Apr 15;18(4):173-178. doi: 10.62347/NZTK3263. eCollection 2025.

Abstract

Intraductal papillary mucinous neoplasm of the bile duct (IPMN-B) is a rare malignant tumor originating from the bile duct epithelium, characterized by its ability to secrete large amounts of mucin, which can lead to biliary obstruction. This paper presents a case involving a 69-year-old woman presenting with intermittent right upper abdominal pain, imaging revealed dilation of the left intrahepatic bile duct and the presence of a solid mass. We performed left lateral hepatectomy on the patient, and the postoperative pathological diagnosis was intraductal papillary tumor with associated invasive carcinoma. At the 6-month postoperative follow-up, the patient showed no signs of recurrence and was in good condition. This case underscores the high malignant potential of IPMN-B, emphasizing the importance of early surgical resection following diagnosis to achieve a favorable prognosis and improve patient outcomes.

摘要

胆管内乳头状黏液性肿瘤(IPMN-B)是一种起源于胆管上皮的罕见恶性肿瘤,其特征是能够分泌大量黏液,可导致胆道梗阻。本文介绍了一例病例,患者为一名69岁女性,表现为间歇性右上腹疼痛,影像学检查显示左肝内胆管扩张并存在实性肿块。我们对该患者实施了左肝外叶切除术,术后病理诊断为导管内乳头状肿瘤伴浸润性癌。术后6个月随访时,患者无复发迹象,状况良好。该病例强调了IPMN-B的高恶性潜能,凸显了诊断后早期手术切除对于获得良好预后和改善患者结局的重要性。

相似文献

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Intraductal Papillary Mucinous Neoplasm of the Bile Duct: A Case Report.胆管内乳头状黏液性肿瘤:一例报告
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本文引用的文献

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The 2019 WHO classification of tumours of the digestive system.2019年世界卫生组织消化系统肿瘤分类。
Histopathology. 2020 Jan;76(2):182-188. doi: 10.1111/his.13975. Epub 2019 Nov 13.

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