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腹膜后肉瘤的管理与患者生存率

Management of retroperitoneal sarcomas and patient survival.

作者信息

Karakousis C P, Velez A F, Emrich L J

出版信息

Am J Surg. 1985 Sep;150(3):376-80. doi: 10.1016/0002-9610(85)90083-2.

DOI:10.1016/0002-9610(85)90083-2
PMID:4037201
Abstract

Sixty-eight patients with retroperitoneal sarcomas had an estimated 5 year survival rate of 34 percent after initial treatment. Patients with complete resection of the tumor had a 5 year rate of 64 percent and a 7 year rate of 56 percent. The respective survival rates for patients with partial excision were 33 percent and 0 and for those with only a biopsy the survival rates at 5 and 7 years were 10 percent. Radiotherapy with chemotherapy or chemotherapy alone was given to 47 patients. In the treatment of macroscopic tumor, radiotherapy or radiotherapy plus chemotherapy resulted in a 5 year survival rate of 10 percent and chemotherapy alone in a 5 year survival rate of 8 percent. Complete surgical resection is an important part of the management of retroperitoneal sarcomas and, with modern techniques of exposure, should be possible in the majority of patients.

摘要

68例腹膜后肉瘤患者在初始治疗后的估计5年生存率为34%。肿瘤完全切除的患者5年生存率为64%,7年生存率为56%。部分切除患者的相应生存率分别为33%和0%,而仅接受活检的患者5年和7年生存率为10%。47例患者接受了化疗联合放疗或单纯化疗。在治疗肉眼可见肿瘤时,放疗或放疗加化疗的5年生存率为10%,单纯化疗的5年生存率为8%。完整的手术切除是腹膜后肉瘤治疗的重要组成部分,借助现代暴露技术,大多数患者应可实现手术切除。

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