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原发性腹膜后肉瘤——16例报告

Primary retroperitoneal sarcomas--a report of 16 cases.

作者信息

Ho H C, Wu H C, Yang C R, Chang C L, Hwang T I, Chang C H, Ou Y C, Liu T J

机构信息

Section of Urology, Taichung Veterans General Hospital, Taiwan, Republic of China.

出版信息

Gaoxiong Yi Xue Ke Xue Za Zhi. 1991 Aug;7(8):443-7.

PMID:1875467
Abstract

From November 1982 to August 1990, 16 patients with primary retroperitoneal sarcoma were treated in our hospital. The most frequent types of tumor were liposarcoma (6), malignant fibrous histiocytoma (3). The commonest clinical findings were palpable abdominal mass (14/16). In management of these patients; nine patients underwent complete resection of the tumor; three patients underwent partial resection of the tumor and four patients underwent biopsy only. The histology of tumor appeared to have prognostic significance. Patients suffering from liposarcoma (3/5) and malignant fibrous histiocytoma (1/2) survived the longest. With a mean follow up of 25.0 months, the three year overall survival rate of complete resection group was 50 per cent. No patients with partial resection and biopsy only group survive three years and the total three-years overall survival rate was 29%. The mean survival for patients after adjuvant chemotherapy and/or radiotherapy was similar to that after a radical operation alone. The prognosis of primary retroperitoneal sarcoma is grave and complete resection of the tumor as initial treatment seems to provide the only chance of cure for these patients.

摘要

1982年11月至1990年8月,我院共治疗16例原发性腹膜后肉瘤患者。最常见的肿瘤类型为脂肪肉瘤(6例)、恶性纤维组织细胞瘤(3例)。最常见的临床表现是可触及腹部肿块(14/16)。在这些患者的治疗中,9例患者接受了肿瘤全切术,3例患者接受了肿瘤部分切除术,4例患者仅接受了活检。肿瘤组织学表现似乎具有预后意义。脂肪肉瘤患者(3/5)和恶性纤维组织细胞瘤患者(1/2)存活时间最长。平均随访25.0个月,全切术组的三年总生存率为50%。部分切除术组和仅活检组无患者存活三年,三年总生存率为29%。辅助化疗和/或放疗后患者的平均生存期与单纯根治性手术后相似。原发性腹膜后肉瘤预后严重,以肿瘤全切术作为初始治疗似乎是为这些患者提供治愈唯一机会。

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