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天然抗体作为细菌清除的一线辅助者。

Natural antibodies as frontline helpers in bacterial clearance.

作者信息

Araujo David Bruna, Kubes Paul

机构信息

Calvin, Phoebe, and Joan Snyder Institute for Chronic Diseases, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada T2N 1N4.

Department of Physiology and Pharmacology, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada T2N 1N4.

出版信息

J Leukoc Biol. 2025 May 7;117(5). doi: 10.1093/jleuko/qiaf028.

Abstract

Mechanism of encapsulated bacteria recognition and capture by Kupffer cells.

摘要

库普弗细胞识别和捕获包膜细菌的机制。

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CRIg Functions as a Macrophage Pattern Recognition Receptor to Directly Bind and Capture Blood-Borne Gram-Positive Bacteria.
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Natural antibodies bridge innate and adaptive immunity.
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An intravascular immune response to Borrelia burgdorferi involves Kupffer cells and iNKT cells.
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