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天然抗体作为细菌清除的一线辅助者。

Natural antibodies as frontline helpers in bacterial clearance.

作者信息

Araujo David Bruna, Kubes Paul

机构信息

Calvin, Phoebe, and Joan Snyder Institute for Chronic Diseases, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada T2N 1N4.

Department of Physiology and Pharmacology, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada T2N 1N4.

出版信息

J Leukoc Biol. 2025 May 7;117(5). doi: 10.1093/jleuko/qiaf028.


DOI:10.1093/jleuko/qiaf028
PMID:40372771
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12080360/
Abstract

Mechanism of encapsulated bacteria recognition and capture by Kupffer cells.

摘要

库普弗细胞识别和捕获包膜细菌的机制。

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[1]
Natural antibodies as frontline helpers in bacterial clearance.

J Leukoc Biol. 2025-5-7

[2]
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[3]
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[4]
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[5]
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[6]
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[7]
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[8]
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[9]
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[10]
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本文引用的文献

[1]
Natural antibodies to polysaccharide capsules enable Kupffer cells to capture invading bacteria in the liver sinusoids.

J Exp Med. 2025-2-3

[2]
Kupffer cell reverse migration into the liver sinusoids mitigates neonatal sepsis and meningitis.

Sci Immunol. 2024-11

[3]
Programing of an Intravascular Immune Firewall by the Gut Microbiota Protects against Pathogen Dissemination during Infection.

Cell Host Microbe. 2020-11-11

[4]
Sex-hormone-driven innate antibodies protect females and infants against EPEC infection.

Nat Immunol. 2018-9-24

[5]
Measurement of bacterial capture and phagosome maturation of Kupffer cells by intravital microscopy.

Methods. 2017-5-15

[6]
CRIg Functions as a Macrophage Pattern Recognition Receptor to Directly Bind and Capture Blood-Borne Gram-Positive Bacteria.

Cell Host Microbe. 2016-6-23

[7]
Natural antibodies bridge innate and adaptive immunity.

J Immunol. 2015-1-1

[8]
An intravascular immune response to Borrelia burgdorferi involves Kupffer cells and iNKT cells.

Nat Immunol. 2010-3-14

[9]
Liver endocytosis and Kupffer cells.

Hepatology. 1992-7

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