Marczylo Emma L, Jackson Simon, Bell Christine, Andrews Daniel, Clift Martin J D, Crawford Ian, Fejer Gyorgy, Ferguson Robert M W, Fisher Matthew C, Goode Emma-Jane, Isaac James, Kinnersley Rob, Morrissey Julie A, Pozdniakova Sofya, Viegas Carla, Ward Andrew, Wouters Inge M, Coulon Frederic, Nasir Zaheer A, Douglas Philippa
Radiation, Chemical and Environmental Hazards Directorate, UK Health Security Agency, Harwell Campus, Chilton, Oxfordshire, OX11 0RQ, UK.
Centre for Environmental Health and Sustainability, University of Leicester, University Road, Leicester, LE1 7RH, UK.
Microbiology (Reading). 2025 May;171(5). doi: 10.1099/mic.0.001561.
We are surrounded, in both indoor and outdoor environments, by air containing particles of biological origin (bioaerosols). We constantly inhale them, and, depending upon their size, they deposit in different parts of our airways. Despite their ubiquitous nature and our constant exposure, bioaerosol diversity and composition of the environment are not well characterized, and we understand little about which bioaerosols we are exposed to and how this impacts our health, either positively or negatively. Indoor/Outdoor Bioaerosols Interface and Relationships Network (BioAirNet), a Clean Air Programme-funded network, has recognized the need for the bioaerosol community to reflect on the current challenges facing bioaerosol exposure assessment and the determination of the associated cellular/molecular responses driving specific health outcomes. A series of online workshops for the bioaerosol community were hosted by BioAirNet in September 2022, which aimed to bring together global expertise to discuss the current challenges impeding improved assessment of bioaerosol exposure and understanding of the downstream cellular and molecular mechanisms driving health outcomes by discussing these challenges; considering where we need to be, where we are now and how we get there. Professional facilitation was key to their success, enabling the multidisciplinary bioaerosol community to explore and address these challenges within a focused and productive environment to prioritize themes and agree on action plans for continued momentum following the workshops. These themes were as follows: (1) conceptual model; (2) stakeholder mapping; (3) knowledge transfer; (4) writing project and (5) conference-type event, collectively covering research, knowledge mobilization and networking activities. A subsequent in-person follow-up workshop was held in November 2023. It provided an opportunity to share progress on the five themes, critique what had already been done and act as a launch-pad to progress the actions further. Delegates also had the opportunity to share ongoing or upcoming work, particularly projects requiring input from others, to encourage collaborative working and sharing expertise. The use of facilitated workshops is a valuable tool for all scientific communities to collectively explore and successfully address key issues within their field.
无论是在室内还是室外环境中,我们都被含有生物源颗粒(生物气溶胶)的空气所包围。我们不断吸入这些颗粒,并且根据它们的大小,它们会沉积在我们呼吸道的不同部位。尽管生物气溶胶具有普遍存在的特性且我们持续暴露于其中,但环境中生物气溶胶的多样性和组成尚未得到很好的表征,我们对自己接触到哪些生物气溶胶以及这如何对我们的健康产生正面或负面影响知之甚少。室内/室外生物气溶胶界面与关系网络(BioAirNet)是一个由清洁空气计划资助的网络,它认识到生物气溶胶领域有必要反思生物气溶胶暴露评估以及确定驱动特定健康结果的相关细胞/分子反应目前面临的挑战。2022年9月,BioAirNet为生物气溶胶领域举办了一系列在线研讨会,旨在汇聚全球专业知识,通过讨论这些挑战来探讨当前阻碍生物气溶胶暴露评估改进以及对驱动健康结果的下游细胞和分子机制理解的挑战;思考我们需要达到的目标、我们目前的状况以及如何实现目标。专业的引导是这些研讨会成功的关键,使多学科的生物气溶胶领域能够在一个专注且富有成效的环境中探索和应对这些挑战,以确定主题优先级并就研讨会之后持续推进的行动计划达成一致。这些主题如下:(1)概念模型;(2)利益相关者映射;(3)知识转移;(4)写作项目;(5)会议类活动,共同涵盖研究、知识传播和网络活动。随后在2023年11月举行了一次线下后续研讨会。它提供了一个分享五个主题进展情况、对已完成工作进行批评并作为进一步推进行动的跳板的机会。与会代表还有机会分享正在进行或即将开展的工作,特别是需要他人投入的项目,以鼓励合作并分享专业知识。对于所有科学领域而言,使用引导式研讨会都是一种有价值的工具,可用于共同探索并成功解决其领域内的关键问题。