Tan Annabel X, Chang Andrew Y, Shimbo Daichi, Bress Adam, Sims Mario, Odden Michelle C
Department of Epidemiology and Population Health, Stanford University, Stanford, CA, USA.
Section of Cardiovascular Medicine, Department of Medicine, Yale University, New Haven, CT, USA.
J Hum Hypertens. 2025 May 15. doi: 10.1038/s41371-025-01026-4.
Extreme temperature events related to climate change may impact blood pressure (BP). African American populations are disproportionately affected by temperature extremes due to structural inequities. We examined the association between ambient outdoor temperature and BP among participants in JHS, a cohort of African American adults residing in the tri-county area of Jackson, Mississippi. Our primary hypothesis is that daily higher outdoor ambient temperatures would be associated with lower BP. We used a linear-mixed effects model to determine the relationship between temperature and systolic and diastolic blood pressure (SBP and DBP) at three visits (N = 5296). Participants had BP readings across three visits: Visit 1 (2000-2004), Visit 2 (2005-2008), Visit 3 (2009-2013). Cardiovascular disease (CVD), diabetes, BP medication, sex, age, and visit number were included as adjustment variables. For every 1-degree Celsius higher average temperature from the mean, SBP was 0.11 mm Hg lower (95% CI: -0.14, -0.07, p < 0.001) in adjusted models. Similarly, for every 1-degree Celsius higher average temperature from the mean, DBP was 0.06 mm Hg lower (95% CI: -0.08, -0.04) in adjusted models. The associations were weakly curvilinear (inverted U-shape) with significant quadratic terms. This relationship was not modified by markers of socioeconomic status. This is the first study in the Jackson Heart Study (JHS) to investigate the association between temperature and blood pressure. Further research is needed to explore this relationship in vulnerable populations living in areas prone to extreme temperatures.
与气候变化相关的极端温度事件可能会影响血压(BP)。由于结构性不平等,非裔美国人群体受极端温度的影响尤为严重。我们在杰克逊心脏研究(JHS)中调查了环境室外温度与血压之间的关联,JHS是一个居住在密西西比州杰克逊三县地区的非裔美国成年人队列。我们的主要假设是,每日较高的室外环境温度会与较低的血压相关。我们使用线性混合效应模型来确定三次访视(N = 5296)时温度与收缩压和舒张压(SBP和DBP)之间的关系。参与者在三次访视中都进行了血压测量:访视1(2000 - 2004年)、访视2(2005 - 2008年)、访视3(2009 - 2013年)。心血管疾病(CVD)、糖尿病、血压药物治疗、性别、年龄和访视次数作为调整变量。在调整模型中,平均温度每比均值高1摄氏度,收缩压降低0.11毫米汞柱(95%置信区间:-0.14,-0.07,p < 0.001)。同样,在调整模型中,平均温度每比均值高1摄氏度,舒张压降低0.06毫米汞柱(95%置信区间:-0.08,-0.04)。这种关联呈弱曲线关系(倒U形),二次项显著。这种关系未被社会经济地位指标所改变。这是杰克逊心脏研究(JHS)中第一项调查温度与血压之间关联的研究。需要进一步研究以探讨生活在易受极端温度影响地区的脆弱人群中的这种关系。