Zhang Yaru, He Yuqiong, Xue Zhenpeng, Xu Jianchang, Sun Yumeng, Song Shiqi, Lin Ling, Lu Jianping, Luo Xuerong, Liu Jianbo
Department of Psychiatry, National Clinical Research Center for Mental Disorders, and National Center for Mental Disorders, the Second Xiangya Hospital of Central South University, Changsha, Hunan, 410011, China.
Department of Child Psychiatry of Shenzhen Kangning Hospital, Shenzhen Clinical Research Center for Mental Disorders, Shenzhen Mental Health Center, Shenzhen, 518003, China.
BMC Public Health. 2025 May 15;25(1):1795. doi: 10.1186/s12889-025-22613-7.
This study aimed to explore the effect of maternal exposure to cumulative childhood trauma (CT) on offspring CT and depressive symptoms.
A total of 3672 mothers and their 3672 adolescent offspring who completed the questionnaires were included in this study. CT was assessed using the Childhood Trauma Questionnaire Short Form, while depressive symptoms in adolescents were assessed using the Center for Epidemiological Studies Depression Scale.
Among the 3672 maternal respondents, 1397 (38.04%) reported ever having experienced CT and 463 (12.61%) reported ≥ 2 types of CT. As shown by logistic regression analysis, having a mother who was exposed to 1 or ≥ 2 types of CT was a risk factor for offspring CT exposure in the overall sample of adolescents, as well as male and female adolescent subgroups, relative to those whose mothers were not exposed to CT. Offspring emotional neglect mediated the relationship between maternal exposure to cumulative CT and offspring depressive symptoms among male and female adolescents, while offspring physical neglect mediated the relationship between maternal exposure to cumulative CT and offspring depressive symptoms among male adolescent offspring, as the indirect paths did not include 0.
Maternal exposure to cumulative CT may affect the severity of CT in their adolescent offspring, which indirectly impacts adolescents' depressive symptoms.
本研究旨在探讨母亲暴露于童年累积创伤(CT)对后代CT及抑郁症状的影响。
本研究纳入了3672名完成问卷调查的母亲及其3672名青少年后代。使用儿童创伤问卷简表评估CT,使用流行病学研究中心抑郁量表评估青少年的抑郁症状。
在3672名母亲受访者中,1397名(38.04%)报告曾经历过CT,463名(12.61%)报告经历过≥2种类型的CT。逻辑回归分析显示,在青少年总体样本以及男性和女性青少年亚组中,母亲暴露于1种或≥2种类型的CT是后代CT暴露的危险因素,相对于其母亲未暴露于CT的青少年。在男性和女性青少年中,后代情感忽视介导了母亲暴露于累积CT与后代抑郁症状之间的关系,而在男性青少年后代中,后代身体忽视介导了母亲暴露于累积CT与后代抑郁症状之间的关系,因为间接路径不包括0。
母亲暴露于累积CT可能会影响其青少年后代CT的严重程度,进而间接影响青少年的抑郁症状。