Chao Calvin L, Habash Nicola M, Eskandari Mark K
Department of Surgery, Division of Vascular Surgery, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA.
J Surg Oncol. 2025 Jun;131(8):1679-1682. doi: 10.1002/jso.28150. Epub 2025 May 15.
Aortic sarcoma is a rare and aggressive malignancy with a poor prognosis despite surgical resection and vascular reconstruction. We present a case series of patients with thoracic aortic sarcoma, highlighting three distinct clinical scenarios: primary resection, resection following prior thoracic aortic endograft, and nonoperative management. Our findings underscore key aspects of aortic sarcoma management, including its embolic potential, diagnostic challenges, and surgical considerations, particularly when endograft explant is required. Despite limited survival, we advocate for complete resection and vascular reconstruction with adjunctive chemoradiotherapy when feasible. Multidisciplinary collaboration remains paramount to optimize postoperative outcome in this complex pathology.
主动脉肉瘤是一种罕见且侵袭性强的恶性肿瘤，尽管进行了手术切除和血管重建，预后仍较差。我们展示了一组胸主动脉肉瘤患者的病例系列，突出了三种不同的临床情况：初次切除、先前胸主动脉腔内移植物植入术后的切除以及非手术治疗。我们的研究结果强调了主动脉肉瘤治疗的关键方面，包括其栓塞风险、诊断挑战和手术考量，特别是在需要取出腔内移植物时。尽管生存期有限，但我们主张在可行的情况下进行完整切除和血管重建，并辅助放化疗。多学科协作对于优化这种复杂病理状况下的术后结果仍然至关重要。
