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与合并症相关的口腔病毒、真菌和细菌感染:来自巴西一家转诊中心的病例系列

Oral viral, fungal, and bacterial infections linked to comorbidities: A case series from a Brazilian referral center.

作者信息

Estanho Daniella, do Amaral-Sobrinho Lucas Fellipe, de Lima Fernanda Silva, Contreiras João Pedro Silva, Agostini Michelle, Andrade Natália Silva, de Arruda José Alcides Almeida, Torres Sandra R, de Oliveira Sílvia Paula, de Andrade Bruno Augusto Benevenuto, Tenório Jefferson R

机构信息

Department of Oral Diagnosis and Pathology, School of Dentistry, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil.

Department of Dentistry, School of Dentistry, Universidade Federal de Sergipe, Sergipe, Brazil.

出版信息

J Clin Exp Dent. 2025 Apr 1;17(4):e382-e392. doi: 10.4317/jced.62619. eCollection 2025 Apr.

DOI:10.4317/jced.62619
PMID:40375845
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12077827/
Abstract

BACKGROUND

Oral infections exhibit variability in their causative agents and clinical presentations, underscoring the necessity of accurate diagnosis for effective management. Despite extensive documentation globally, data on these infections from Brazil remain scarce. This study aimed to assess the occurrence, clinical features, and differential diagnosis of oral viral, fungal, and bacterial infections at a single center in southern Brazil.

MATERIAL AND METHODS

A retrospective analysis was conducted between 2010 and 2023. Clinicodemographic data, comorbidities, and routine medication use were analyzed descriptively and statistically.

RESULTS

A total of 462 cases were included. The median age was 49.5 years (range: 2-100). Viral infections were the most frequent (65.8%), with squamous papilloma accounting for 49.4% of cases. Fungal infections comprised 29.4% of cases, predominantly erythematous candidiasis (20.8%) and pseudomembranous candidiasis (5.6%). These infections were more common in women, older adults (<0.001), and individuals with comorbidities such as systemic arterial hypertension (=0.006) and diabetes mellitus (=0.028). Bacterial infections were rare (4.8%), with actinomycosis being the most frequent (2.2%).

CONCLUSIONS

Data from our series on oral viral, fungal, and bacterial infections align with the literature. The results emphasize the importance of tailored diagnostic approaches, particularly for at-risk patient populations. Bacterial infections, Communicable diseases, Mycoses, Oral manifestations, Virus diseases.

摘要

背景

口腔感染的病原体和临床表现存在差异,这凸显了准确诊断以进行有效管理的必要性。尽管全球已有大量文献记载,但来自巴西的这些感染数据仍然稀缺。本研究旨在评估巴西南部单一中心口腔病毒、真菌和细菌感染的发生率、临床特征及鉴别诊断。

材料与方法

对2010年至2023年期间进行回顾性分析。对临床人口统计学数据、合并症和常规用药情况进行描述性和统计学分析。

结果

共纳入462例病例。中位年龄为49.5岁(范围:2 - 100岁)。病毒感染最为常见(65.8%),其中鳞状乳头状瘤占病例的49.4%。真菌感染占病例的29.4%,主要为红斑型念珠菌病(20.8%)和假膜型念珠菌病(5.6%)。这些感染在女性、老年人(<0.001)以及患有全身性动脉高血压(=0.006)和糖尿病(=0.028)等合并症的个体中更为常见。细菌感染较少见(4.8%),放线菌病最为常见(2.2%)。

结论

我们关于口腔病毒、真菌和细菌感染系列的数据与文献相符。结果强调了针对性诊断方法的重要性,特别是对于高危患者群体。细菌感染、传染病、真菌病、口腔表现、病毒病。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b225/12077827/02010034084f/jced-17-e382-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b225/12077827/6c6fab9c430f/jced-17-e382-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b225/12077827/5ffd17e7fca9/jced-17-e382-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b225/12077827/e2d31d85edc9/jced-17-e382-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b225/12077827/02010034084f/jced-17-e382-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b225/12077827/6c6fab9c430f/jced-17-e382-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b225/12077827/5ffd17e7fca9/jced-17-e382-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b225/12077827/e2d31d85edc9/jced-17-e382-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b225/12077827/02010034084f/jced-17-e382-g004.jpg

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