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Thalidomide Treatment for Thrombocytopenia Secondary to Hypersplenism in Children with Transfusion-Dependent β-Thalassemia: A Case Series.

作者信息

Gong Xiaoqing, Xiao Jian, Kong Wenqiang, Liu Xiaodong, Yang Kun

机构信息

Department of Pharmacy, Zigong First People's Hospital, Zigong, China.

Department of Hematology, Zigong First People's Hospital, Zigong, China.

出版信息

Mediterr J Hematol Infect Dis. 2025 May 1;17(1):e2025037. doi: 10.4084/MJHID.2025.037. eCollection 2025.

DOI:10.4084/MJHID.2025.037
PMID:40375905
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12081042/
Abstract
摘要

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1
Thalidomide Treatment for Thrombocytopenia Secondary to Hypersplenism in Children with Transfusion-Dependent β-Thalassemia: A Case Series.沙利度胺治疗依赖输血的β地中海贫血患儿脾功能亢进继发血小板减少症:病例系列
Mediterr J Hematol Infect Dis. 2025 May 1;17(1):e2025037. doi: 10.4084/MJHID.2025.037. eCollection 2025.
2
Thalidomide for the Treatment of Thrombocytopenia and Hypersplenism in Patients With Cirrhosis or Thalassemia.沙利度胺用于治疗肝硬化或地中海贫血患者的血小板减少症和脾功能亢进。
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Front Pharmacol. 2021 Aug 12;12:722502. doi: 10.3389/fphar.2021.722502. eCollection 2021.
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本文引用的文献

1
Effects of Thalidomide on Endothelial Activation and Stress Index in Children with β-Thalassemia Major.沙利度胺对重型β地中海贫血患儿内皮细胞活化及应激指标的影响
Mediterr J Hematol Infect Dis. 2024 Nov 1;16(1):e2024076. doi: 10.4084/MJHID.2024.076. eCollection 2024.
2
Effects of Thalidomide on Erythropoiesis and Iron Homeostasis in Transfusion-Dependent β-Thalassemia.沙利度胺对依赖输血的β地中海贫血患者红细胞生成及铁稳态的影响
Mediterr J Hematol Infect Dis. 2024 Jan 1;16(1):e2024001. doi: 10.4084/MJHID.2024.001. eCollection 2024.
3
Clinical Classification, Screening, and Diagnosis in Beta-Thalassemia and Hemoglobin E/Beta-Thalassemia.
β-地中海贫血和血红蛋白 E/β-地中海贫血的临床分类、筛查和诊断。
Hematol Oncol Clin North Am. 2023 Apr;37(2):313-325. doi: 10.1016/j.hoc.2022.12.003.
4
Thalassaemia.地中海贫血症。
Lancet. 2022 Jun 18;399(10343):2310-2324. doi: 10.1016/S0140-6736(22)00536-0. Epub 2022 Jun 9.
5
Magnetic Resonance Imaging Quantification of the Liver Iron Burden and Volume Changes Following Treatment With Thalidomide in Patients With Transfusion-Dependent -Thalassemia.沙利度胺治疗依赖输血的β地中海贫血患者后肝脏铁负荷及体积变化的磁共振成像定量分析
Front Pharmacol. 2022 Feb 18;13:810668. doi: 10.3389/fphar.2022.810668. eCollection 2022.
6
Safety and efficacy of thalidomide in patients with transfusion-dependent β-thalassemia: a randomized clinical trial.沙利度胺治疗输血依赖型β-地中海贫血患者的安全性和有效性:一项随机临床试验。
Signal Transduct Target Ther. 2021 Nov 18;6(1):405. doi: 10.1038/s41392-021-00811-0.
7
Thalidomide for the Treatment of Thrombocytopenia and Hypersplenism in Patients With Cirrhosis or Thalassemia.沙利度胺用于治疗肝硬化或地中海贫血患者的血小板减少症和脾功能亢进。
Front Pharmacol. 2020 Jul 24;11:1137. doi: 10.3389/fphar.2020.01137. eCollection 2020.
8
Thalidomide prevents antibody-mediated immune thrombocytopenia in mice.沙利度胺可预防小鼠抗体介导的免疫性血小板减少症。
Thromb Res. 2019 Nov;183:69-75. doi: 10.1016/j.thromres.2019.09.035. Epub 2019 Oct 22.
9
Thrombocytopenia: an update.血小板减少症:最新进展。
Int J Lab Hematol. 2014 Jun;36(3):269-78. doi: 10.1111/ijlh.12214.
10
The importance of spleen, spleen iron, and splenectomy for determining total body iron load, ferrikinetics, and iron toxicity in thalassemia major patients.脾脏、脾铁和脾切除术在确定地中海贫血患者体内总铁负荷、铁代谢动力学和铁毒性中的重要性。
Toxicol Mech Methods. 2013 Jan;23(1):34-41. doi: 10.3109/15376516.2012.735278.