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1例非典型隐球菌性脑膜炎合并吉兰-巴雷综合征的罕见病例及文献复习

A Rare Case of Atypical Cryptococcal Meningitis Comorbid With Guillain-Barré Syndrome and Literature Review.

作者信息

Yang Liu L, Sun Zhou, Fang Zhi, Zhang Lei, Xia Yuanpeng

机构信息

Department of Neurology Union Hospital, Huazhong University of Science and Technology, Tongji Medical College Wuhan China.

出版信息

Clin Case Rep. 2025 May 15;13(5):e70512. doi: 10.1002/ccr3.70512. eCollection 2025 May.

DOI:10.1002/ccr3.70512
PMID:40376203
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12079341/
Abstract

Cryptococcal meningitis in non-HIV patients and comorbid with Guillain-Barré syndrome is rare. Accurate diagnosis necessitates a comprehensive understanding of historical records, laboratory workup, and a heightened index of suspicion, coupled with prompt and comprehensive combined therapy.

摘要

非HIV患者合并吉兰-巴雷综合征的隐球菌性脑膜炎较为罕见。准确诊断需要全面了解病史、实验室检查结果，并提高怀疑指数，同时要迅速进行全面的联合治疗。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6c4b/12079341/148a81dc4ee3/CCR3-13-e70512-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6c4b/12079341/045654ec3bcf/CCR3-13-e70512-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6c4b/12079341/c1f5b468038f/CCR3-13-e70512-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6c4b/12079341/148a81dc4ee3/CCR3-13-e70512-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6c4b/12079341/045654ec3bcf/CCR3-13-e70512-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6c4b/12079341/c1f5b468038f/CCR3-13-e70512-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6c4b/12079341/148a81dc4ee3/CCR3-13-e70512-g003.jpg

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本文引用的文献

1
Cryptococcal meningitis.隐球菌性脑膜炎
Nat Rev Dis Primers. 2023 Nov 9;9(1):62. doi: 10.1038/s41572-023-00472-z.
2
Characteristics of Guillain-Barré syndrome in super-elderly individuals.超高龄个体吉兰-巴雷综合征的特征
J Neurol. 2023 Apr;270(4):2191-2196. doi: 10.1007/s00415-023-11567-8. Epub 2023 Jan 16.
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Cryptococcal meningitis in apparently immunocompetent patients.隐球菌性脑膜炎在貌似免疫健全的患者中。
Crit Rev Microbiol. 2024 Feb;50(1):76-86. doi: 10.1080/1040841X.2022.2159786. Epub 2022 Dec 23.
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Old age and multiple comorbidity are associated with delayed diagnosis of Guillain-Barre syndrome.老年和多种合并症与吉兰-巴雷综合征的延迟诊断相关。
Sci Rep. 2022 Jun 15;12(1):9913. doi: 10.1038/s41598-022-14184-z.
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Investigating the Long-Term Effect of an Interdisciplinary Multimodal Rehabilitation Program on Levels of Bioactive Lipids and Telomerase Activity in Blood from Patients with Chronic Pain.探究跨学科多模式康复计划对慢性疼痛患者血液中生物活性脂质水平和端粒酶活性的长期影响。
J Clin Med. 2022 Feb 26;11(5):1291. doi: 10.3390/jcm11051291.
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Disseminated Cryptococcal Disease in A Patient With Chronic Chylothorax and a Pleurovenous Catheter, a Case Report With Autopsy Findings.一名慢性乳糜胸患者及带有胸膜静脉导管的播散性隐球菌病：一份伴有尸检结果的病例报告
Open Forum Infect Dis. 2021 May 19;8(6):ofab258. doi: 10.1093/ofid/ofab258. eCollection 2021 Jun.
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Guillain-Barré syndrome.格林-巴利综合征。
Lancet. 2021 Mar 27;397(10280):1214-1228. doi: 10.1016/S0140-6736(21)00517-1. Epub 2021 Feb 26.
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COVID-19 Infection and Neurological Complications: Present Findings and Future Predictions.新型冠状病毒肺炎感染与神经系统并发症：现有研究结果与未来预测。
Neuroepidemiology. 2020;54(5):364-369. doi: 10.1159/000508991. Epub 2020 Jul 1.
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Diagnosis and management of Guillain-Barré syndrome in ten steps.吉兰-巴雷综合征的诊断和管理十步骤。
Nat Rev Neurol. 2019 Nov;15(11):671-683. doi: 10.1038/s41582-019-0250-9. Epub 2019 Sep 20.
10
Guillain-Barré syndrome, transverse myelitis and infectious diseases.格林-巴利综合征、横断性脊髓炎和传染病。
Cell Mol Immunol. 2018 Jun;15(6):547-562. doi: 10.1038/cmi.2017.142. Epub 2018 Jan 29.