文献检索文档翻译深度研究
Suppr Zotero 插件Zotero 插件
邀请有礼套餐&价格历史记录

新学期,新优惠

限时优惠:9月1日-9月22日

30天高级会员仅需29元

1天体验卡首发特惠仅需5.99元

了解详情
不再提醒
插件&应用
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
高级版
套餐订阅购买积分包
AI 工具
文献检索文档翻译深度研究
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2025

Advances in bladder preservation therapy for muscle-invasive bladder cancer.

作者信息

Zhang Ran, Ke Chang-Xing

机构信息

Department of Urology, The Second Affiliated Hospital of Kunming Medical University, Kunming, China.

出版信息

Front Oncol. 2025 May 1;15:1562260. doi: 10.3389/fonc.2025.1562260. eCollection 2025.


DOI:10.3389/fonc.2025.1562260
PMID:40376576
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12078131/
Abstract

Bladder cancer is one of the most common genitourinary malignancies. Radical cystectomy (RC) and pelvic lymphadenectomy (PLND) after neoadjuvant chemotherapy have become the accepted gold standard for the treatment of resectable muscular invasive bladder cancer due to its ability to surgically remove tumor tissue as thoroughly as possible and reduce the risk of tumor recurrence and metastasis, thus improving patient survival. However, RC surgery is challenging and associated with many postoperative complications, requiring patients to have good physical condition to tolerate the procedure. Over the years, with the deepening of medical research and the accumulation of clinical practice, the disease spectrum of bladder cancer has changed significantly. At the same time, the treatment modalities for bladder cancer have also been continuously improved and updated, and bladder-preserving treatment programs have gradually emerged and demonstrated reliable efficacy. Bladder-sparing treatment aims to preserve the physiological function of the bladder while controlling tumor growth, thereby improving patients' quality of life. This approach has led an increasing number of MIBC patients to choose bladder-sparing treatment after considering their individual conditions. In this paper, we review the current methods of bladder-sparing treatment for MIBC patients and related studies to provide a reference for future research.

摘要

相似文献

[1]
Advances in bladder preservation therapy for muscle-invasive bladder cancer.

Front Oncol. 2025-5-1

[2]
ICUD-EAU International Consultation on Bladder Cancer 2012: Radical cystectomy and bladder preservation for muscle-invasive urothelial carcinoma of the bladder.

Eur Urol. 2012-8-14

[3]
Organ-Sparing Strategies in Muscle-Invasive Bladder Cancer.

Cancer Manag Res. 2021-10-13

[4]
Quality indicators for the management of muscle-invasive bladder cancer in the perioperative setting of radical cystectomy: a narrative review.

Transl Cancer Res. 2022-4

[5]
Impact of Immune and Stromal Infiltration on Outcomes Following Bladder-Sparing Trimodality Therapy for Muscle-Invasive Bladder Cancer.

Eur Urol. 2019-2-1

[6]
Trimodality Therapy Versus Radical Cystectomy for Muscle-invasive Bladder Cancer: A Systematic Review and Meta-analysis of Matched Cohort Studies.

Eur Urol Focus. 2024-11-21

[7]
Evaluating the efficacy and safety of bladder-sparing regimen with Disitamab Vedotin combined with Toripalimab and pelvic lymph node dissection in muscle-invasive bladder cancer patients: study protocol of a multicenter single-arm phase II trial.

BMC Cancer. 2025-5-13

[8]
Extended versus standard lymph node dissection for urothelial carcinoma of the bladder in patients undergoing radical cystectomy.

Cochrane Database Syst Rev. 2019-5-14

[9]
Selective tetramodal bladder-preservation therapy, incorporating induction chemoradiotherapy and consolidative partial cystectomy with pelvic lymph node dissection for muscle-invasive bladder cancer: oncological and functional outcomes of 107 patients.

BJU Int. 2019-4-3

[10]
Meta-analysis of neoadjuvant chemotherapy compared to radical cystectomy alone in improving overall survival of muscle-invasive bladder cancer patients.

BMC Urol. 2020-10-14

引用本文的文献

[1]
Cytotoxicity of Pb-labeled anti-PTK7 antibody in 2D adherent and 3D multicellular bladder cancer models.

EJNMMI Radiopharm Chem. 2025-8-30

本文引用的文献

[1]
Trimodality therapy versus radical cystectomy for muscle-invasive bladder cancer: A systematic review and meta-analysis.

Urol Oncol. 2025-7

[2]
Artificial intelligence application in the diagnosis and treatment of bladder cancer: advance, challenges, and opportunities.

Front Oncol. 2024-11-7

[3]
Phase 3 THOR Japanese subgroup analysis: erdafitinib in advanced or metastatic urothelial cancer and fibroblast growth factor receptor alterations.

Int J Clin Oncol. 2024-10

[4]
Real-world effectiveness and safety of RC48-ADC alone or in combination with PD-1 inhibitors for patients with locally advanced or metastatic urothelial carcinoma: A multicenter, retrospective clinical study.

Cancer Med. 2023-12

[5]
Pembrolizumab with Chemoradiation as Treatment for Muscle-invasive Bladder Cancer: Analysis of Safety and Efficacy of the PCR-MIB Phase 2 Clinical Trial (ANZUP 1502).

Eur Urol Oncol. 2024-6

[6]
Disitamab vedotin in combination with immune checkpoint inhibitors for locally and locally advanced bladder urothelial carcinoma: a two-center's real-world study.

Front Pharmacol. 2023-8-14

[7]
Clinical application and efficacy analysis of partial cystectomy combined with intravesical chemotherapy in muscle-invasive bladder cancer.

BMC Urol. 2023-5-11

[8]
NCCN Guidelines® Insights: Bladder Cancer, Version 2.2022.

J Natl Compr Canc Netw. 2022-8

[9]
Neoadjuvant Treatment in Muscle-Invasive Bladder Cancer: From the Beginning to the Latest Developments.

Front Oncol. 2022-7-22

[10]
CT-based radiomics to predict muscle invasion in bladder cancer.

Eur Radiol. 2022-5

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

推荐工具

医学文档翻译智能文献检索