[Effects of septal lesions on the response of vasopressin to angiotensin II].

Electrolytic lesion of the medio-ventral septal (MVS) area produces a sustained increase in daily water intake and urine output. This polyuria and hyperdipsia are associated with decreased levels of circulating radioimmunoassayable ADH. In addition, the usual ADH release to angiotensin II observed in normal controls and sham-lesioned rats was markedly blunted in MVS-lesioned animals.