氯喹引起的毛发和雀斑色素减退。与先天性肾衰竭的关联。

Chloroquine-induced hypopigmentation of hair and freckles. Association with congenital renal failure.

作者信息

Dupré A, Ortonne J P, Viraben R, Arfeux F

出版信息

Arch Dermatol. 1985 Sep;121(9):1164-6. doi: 10.1001/archderm.1985.01660090078018.

DOI:10.1001/archderm.1985.01660090078018

Abstract

Hypopigmentation of hair and freckles occurred in a patient receiving chloroquine sulfate therapy. This patient had a severe congenital renal failure that presumably increased plasma and tissue levels of the drug substantially, accounting for the hypopigmentation.

摘要

一名接受硫酸氯喹治疗的患者出现了毛发色素减退和雀斑。该患者患有严重的先天性肾衰竭，这可能大幅提高了药物的血浆和组织水平，从而导致色素减退。