Pan Xiaoqiang, Li Jiajia, Liu Panbo, Li Jin, Zhao Mingyue, Wu Yulun, Ji Shuyu, Ren Tong, Jiang Qiuhua, Zhang Songling
Department of Neurosurgery, The First Hospital of Jilin University, Changchun, Jilin, 130012, China; Department of Neurosurgery, Ganzhou People's Hospital, Ganzhou, Jiangxi, 341000, China.
Department of Gynecologic Oncology, Gynecology and Obstetrics Centre, The First Hospital of Jilin University, Changchun, Jilin, 130012, China; Jilin Provincial Key Laboratory of Female Reproductive Health, Changchun, Jilin, 130012, China.
Comput Biol Med. 2025 Jun;192(Pt B):110362. doi: 10.1016/j.compbiomed.2025.110362. Epub 2025 May 15.
Currently, many studies have shown that there is a link between metabolic syndrome (MetS) and endometrial cancer (EC). However, there has been no systematic bibliometric analysis of related publications, which limits the comprehensive understanding of research trends and priorities. Our study makes up for this problem.
Through bibliometric analysis, this study aimed to reveal key research focus areas, developmental trends, and major contributors of EC and MetS.
The literature for this study was obtained from the Web of Science Core Collection (WoSCC) through August 31, 2024. We searched for EC and MetS using subject and free terms. Microsoft Office Excel 2016, CiteSpace, and VOSviewer software packages were used for bibliometric analysis, considering specific characteristics such as year of publication, country, institution, authorship, journal, references, and keywords.
A total of 367 publications were included. Annual publications exhibited exponential growth (R2 = 0.8282), indicatingsustained interest in the field. The United States (111 publications), China (80), and Italy (38) were the most productive countries. The University of California System led institutional contributions. Keyword co-occurrence and burst analysis revealed that obesity (occurrence: 113; link strength: 630), insulin resistance (112; 587), and polycystic ovary syndrome (83; 386) were the most frequent and interconnected research foci. Emerging trends, identified through keyword time-zone mapping (average citation year: 2015-2019), highlighted weight control and bariatric surgery as novel interventions. Journals with the highest impact included ∗Fertility and Sterility∗ (IF: 6.6) and ∗International Journal of Epidemiology (IF: 6.4).
This study conducted a preliminary bibliometric and visual analysis of the EC and MetS research literature, revealing trends, global cooperation models, fundamental knowledge, and emerging frontiers of EC and MetS. For over 30 years, research has mainly focused on the correlation between MetS and EC, disease factors, prognosis, prevention, and other aspects that have guiding significance for public health.
目前，许多研究表明代谢综合征（MetS）与子宫内膜癌（EC）之间存在联系。然而，尚未对相关出版物进行系统的文献计量分析，这限制了对研究趋势和重点的全面理解。我们的研究弥补了这一问题。
通过文献计量分析，本研究旨在揭示子宫内膜癌和代谢综合征的关键研究重点领域、发展趋势以及主要贡献者。
本研究的文献通过检索截至2024年8月31日的Web of Science核心合集（WoSCC）获得。我们使用主题词和自由词检索子宫内膜癌和代谢综合征。考虑到出版年份、国家、机构、作者、期刊、参考文献和关键词等特定特征，使用Microsoft Office Excel 2016、CiteSpace和VOSviewer软件包进行文献计量分析。
共纳入367篇出版物。年度出版物呈指数增长（R2 = 0.8282），表明该领域持续受到关注。美国（111篇出版物）、中国（80篇）和意大利（38篇）是产出最多的国家。加利福尼亚大学系统在机构贡献方面领先。关键词共现和突现分析表明，肥胖（出现次数：113；链接强度：630）、胰岛素抵抗（112；587）和多囊卵巢综合征（83；386）是最频繁且相互关联的研究热点。通过关键词时区映射确定的新兴趋势（平均被引年份：2015 - 2019）突出了体重控制和减肥手术作为新的干预措施。影响最大的期刊包括《生育与不孕》（IF：6.6）和《国际流行病学杂志》（IF：6.4）。
本研究对子宫内膜癌和代谢综合征的研究文献进行了初步的文献计量和可视化分析，揭示了子宫内膜癌和代谢综合征的趋势、全球合作模式、基础知识和新兴前沿。30多年来，研究主要集中在代谢综合征与子宫内膜癌的相关性、疾病因素、预后、预防等对公共卫生具有指导意义的方面。
