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为老年抑郁症患者提供的有治疗师支持的量身定制的互联网认知行为疗法:一项为期一年随访的随机对照试验结果

Tailored internet-delivered cognitive behavioral therapy with therapist support for depressed older adults: Results from a randomized controlled trial with a one-year follow-up.

作者信息

Eimontas Jonas, Medeišienė Jogilė, Baranova Karolina, Biliūnaitė Ieva, Pakalniškienė Vilmantė, Zrumaitė Simona, Hilbig Jan, Andersson Gerhard

机构信息

Institute of Psychology, Faculty of Philosophy, Vilnius University, Lithuania.

Institute of Psychology, Faculty of Philosophy, Vilnius University, Lithuania.

出版信息

J Affect Disord. 2025 Sep 15;385:119406. doi: 10.1016/j.jad.2025.119406. Epub 2025 May 14.

Abstract

OBJECTIVES

Internet-delivered cognitive behavioral therapy has been found to be effective for various populations with somatic and psychological difficulties. However, older adults are often overlooked and have received relatively less attention in research. This study aimed to test the effects of an 8-week therapist-supported internet-based cognitive behavioral therapy program for depressed older adults compared to a waiting-list control condition.

METHODS

Individuals interested in participating in the study completed self-report questionnaires online, followed by a semi-structured intake interview. Symptoms of depression were the primary outcome and were measured with the PHQ-9 and GDS-15. Secondary outcome measures included anxiety symptoms (GAD-7) and psychological well-being (WHO-5). In total, 84 help-seeking individuals 60+ years old met the inclusion criteria and were included in the study. They were randomized on a 1:1 ratio to either 8 weeks of guided internet-delivered CBT (ICBT) or to a waiting-list control group.

RESULTS

Results analysed on an intention-to-treat and completer basis after 8 weeks of intervention showed treatment effects in favor of the ICBT group compared to a waiting-list at post-treatment with moderate to large between-group effects. Treatment effects in the treatment group were maintained at 3-months and 1-year follow-ups. Treatment dropout was also associated with older age and with lower computer skills.

CONCLUSIONS

This study suggests that therapist-guided ICBT can be a feasible treatment option for older adults with symptoms of depression.

LIMITATIONS

The main limitations of this study is a small sample size and lack of control group in the follow-up assessments.

摘要

目的

已发现互联网提供的认知行为疗法对有躯体和心理问题的各类人群有效。然而,老年人往往被忽视,在研究中受到的关注相对较少。本研究旨在测试一项为期8周的由治疗师支持的基于互联网的认知行为疗法项目对抑郁老年人的效果,并与等待名单对照组进行比较。

方法

有兴趣参与研究的个体在线完成自我报告问卷,随后进行半结构化的入组访谈。抑郁症状是主要结局,用PHQ - 9和GDS - 15进行测量。次要结局指标包括焦虑症状(GAD - 7)和心理健康状况(WHO - 5)。共有84名年龄在60岁及以上寻求帮助的个体符合纳入标准并被纳入研究。他们以1:1的比例随机分为接受8周有指导的互联网认知行为疗法(ICBT)组或等待名单对照组。

结果

在干预8周后,基于意向性分析和完成者分析的结果显示,与等待名单对照组相比,治疗后ICBT组有治疗效果,组间效应为中度到高度。治疗组的治疗效果在3个月和1年随访时得以维持。治疗退出也与年龄较大和计算机技能较低有关。

结论

本研究表明,由治疗师指导的ICBT对于有抑郁症状的老年人可能是一种可行的治疗选择。

局限性

本研究的主要局限性是样本量小以及随访评估中缺乏对照组。

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