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[汉堡一家大型成瘾诊所中年轻患者当前的阿片类药物消费量:2019年至2023年的比较]

[Current opioid consumption among younger patients : A comparison between the years 2019 and 2023 in a large addiction clinic in Hamburg].

作者信息

Roy Mandy, Strate Peter

机构信息

Klinik für Abhängigkeitserkrankungen, Asklepios Klinik Nord Ochsenzoll, Langenhorner Chaussee 560, 22419, Hamburg, Deutschland.

出版信息

Nervenarzt. 2025 May 16. doi: 10.1007/s00115-025-01833-7.

Abstract

BACKGROUND

It remains unclear whether an opioid crisis similar to that in the United States can be expected in Germany. In September 2024, the federal government stated that it does not see any danger of this occurring in the country. Nevertheless, the number of drug-related deaths in 2023 reached an all-time high of 2227 victims, with opioids involved in 1626 of those cases. For a more comprehensive assessment, information from additional settings may be helpful.

OBJECTIVES

This study aimed to analyze the quantitative development of inpatient treatment cases of younger patients with opioid addiction from a large addiction clinic in Hamburg, as well as their consumption patterns.

MATERIALS AND METHODS

Based on data stored in electronic patient records, a comparison was made of the relative proportions of inpatient patients treated for opioid addiction in the age groups "18-30 years" vs. "≥ 31 years" between the years 2019 and 2023 using chi-square tests. Additionally, the substances consumed were analyzed.

RESULTS

A significant increase in the relative proportion of young opioid-dependent patients was observed, rising from 17.2% in 2019 to 27.5% in 2023 (p < 0.001). Heroin remained the most commonly consumed substance, consistently inhaled or taken nasally. The use of oxycodone increased significantly. Additionally, a significant increase in pregabalin consumption was noted.

CONCLUSIONS

Although the collected data may not be representative of Germany as a whole, our study suggests a growing issue with opioid addiction. Possible causes may include psychological stress, potentially influenced by the aftermath of the COVID-19 pandemic. The results highlight the need for more comprehensive treatment options and preventive measures.

摘要

背景

目前尚不清楚德国是否会出现类似于美国的阿片类药物危机。2024年9月,联邦政府表示该国未发现此类危机发生的任何危险。尽管如此,2023年与毒品相关的死亡人数达到了创纪录的2227人,其中1626例涉及阿片类药物。为了进行更全面的评估,来自其他环境的信息可能会有所帮助。

目的

本研究旨在分析汉堡一家大型戒毒诊所中年轻阿片类药物成瘾患者的住院治疗病例数量变化及其消费模式。

材料与方法

基于电子病历中存储的数据,使用卡方检验比较了2019年至2023年间“18 - 30岁”与“≥31岁”年龄组中因阿片类药物成瘾接受住院治疗的患者相对比例。此外,还对所消费的物质进行了分析。

结果

观察到年轻阿片类药物依赖患者的相对比例显著增加,从2019年的17.2%升至2023年的27.5%(p < 0.001)。海洛因仍然是最常消费的物质,一直通过吸入或鼻吸使用。羟考酮的使用显著增加。此外,还注意到普瑞巴林的消费量显著增加。

结论

尽管所收集的数据可能不代表整个德国,但我们的研究表明阿片类药物成瘾问题日益严重。可能的原因包括心理压力,这可能受到新冠疫情后果的影响。结果凸显了需要更全面的治疗方案和预防措施。

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