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在一个代表性严重不足的少数族裔人群中确定腹疝复发的体重指数阈值。

Determining a BMI threshold for ventral hernia recurrence among a predominantly underrepresented minority population.

作者信息

Cook James L, Purdy Amanda C, Liu Jessica K, Okafor Chinelo, Moazzez Ashkan, Ozao-Choy Junko

机构信息

Department of Surgery, Harbor-UCLA Medical Center, Torrance, CA, 90509, USA.

Loyola Marymount University, Los Angeles, CA, 90045, USA.

出版信息

Hernia. 2025 May 17;29(1):167. doi: 10.1007/s10029-025-03360-5.


DOI:10.1007/s10029-025-03360-5
PMID:40380045
Abstract

PURPOSE: Identify the body mass index (BMI) threshold at which the risk of recurrence increases after hernia repair. METHODS: In this retrospective observational study, clinical data were collected from patients who underwent ventral hernia repair within a county-wide health system from to 2014-2020. Classification and Regression Tree (CART) analysis was used to determine the BMI threshold at which recurrence rate significantly increased. Bivariate and multivariable Cox regression analyses were used to determine the association of the identified threshold and other factors with recurrence. The Kaplan-Meyer analysis described the long-term recurrence risk based on the identified BMI threshold. RESULTS: 478 patients with a median BMI of 32.5 kg/m (IQR = 29.9-36.3) were included. The recurrence rate was 14.4% over a median follow-up interval of 858.5 days (IQR = 138-1252). On CART analysis, BMI > 33.67 kg/m was associated with significantly increased recurrence rates (23.6% vs. 8.4%, p <.001). In the Cox regression analysis, cirrhosis (OR:4.205 [95% CI:1.608-10.995), p =.003], urgent or emergent repair (OR:2.111 [95% CI:1.029-4.332), p =.042], and BMI > 33.67 kg/m [OR:2.179 (95% CI:1.284-3.669), p =.004] were found to be independently associated with recurrence. In addition, patients with a BMI > 33.67 kg/m2 had a statistically significant decrease in the six-year recurrence-free rate (p <.001). CONCLUSIONS: BMI > 33.67 kg/m was the identified threshold at which hernia recurrence rate significantly increased in patients in a large county hospital system who underwent ventral hernia repair, and the risk continued for up to 6 years. A history of cirrhosis and urgent or emergent repair were also found to be independently associated with hernia recurrence.

摘要

目的:确定疝修补术后复发风险增加的体重指数(BMI)阈值。 方法:在这项回顾性观察研究中,收集了2014年至2020年在全县卫生系统内接受腹疝修补术患者的临床数据。使用分类回归树(CART)分析来确定复发率显著增加的BMI阈值。采用双变量和多变量Cox回归分析来确定所确定的阈值及其他因素与复发的关联。Kaplan-Meier分析描述了基于所确定的BMI阈值的长期复发风险。 结果:纳入了478例患者,BMI中位数为32.5kg/m²(四分位间距[IQR]=29.9-36.3)。在中位随访期858.5天(IQR=138-1252)内,复发率为14.4%。CART分析显示,BMI>33.67kg/m²与复发率显著增加相关(23.6%对8.4%,p<0.001)。在Cox回归分析中,肝硬化(比值比[OR]:4.205[95%置信区间:1.608-10.995],p=0.003)、急诊或紧急修补(OR:2.111[95%置信区间:1.029-4.332],p=0.042)以及BMI>33.67kg/m²[OR:2.179(95%置信区间:1.284-3.669),p=0.004]被发现与复发独立相关。此外,BMI>33.67kg/m²的患者六年无复发生存率有统计学显著下降(p<0.001)。 结论:在一家大型县级医院系统中,接受腹疝修补术的患者中,BMI>33.67kg/m²是疝复发率显著增加的确定阈值,且该风险持续长达6年。还发现肝硬化病史以及急诊或紧急修补与疝复发独立相关。

相似文献

[1]
Determining a BMI threshold for ventral hernia recurrence among a predominantly underrepresented minority population.

Hernia. 2025-5-17

[2]
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Am Surg. 2022-10

[3]
Effects of smoking and different BMI cutoff points on surgical site infection after elective open ventral hernia repair.

Hernia. 2021-4

[4]
Laparoscopic ventral hernia repair with composite mesh: Analysis of risk factors for recurrence in 185 patients with 5 years follow-up.

Int J Surg. 2017-2-20

[5]
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Surg Endosc. 2025-3

[6]
Surgical site occurrences, not body mass index, increase the long-term risk of ventral hernia recurrence.

Surgery. 2020-2-13

[7]
Patient profiles and outcomes following repair of irreducible and reducible Ventral Wall Hernias.

Hernia. 2016-4

[8]
Amelioration of the effects of obesity on short-term postoperative complications of laparoscopic and open ventral hernia repair.

Surg Laparosc Endosc Percutan Tech. 2015-4

[9]
Year-Over-Year Ventral Hernia Recurrence Rates and Risk Factors.

JAMA Surg. 2024-6-1

[10]
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引用本文的文献

[1]
Comment to: comparison of short-term clinical efficacy and safety between biological and synthetic meshes in laparoscopic hiatal hernia repair.

Hernia. 2025-5-30

本文引用的文献

[1]
Effects of smoking and different BMI cutoff points on surgical site infection after elective open ventral hernia repair.

Hernia. 2021-4

[2]
Surgical site occurrences, not body mass index, increase the long-term risk of ventral hernia recurrence.

Surgery. 2020-2-13

[3]
Impact of body mass index on open ventral hernia repair: A retrospective review.

Surgery. 2017-12

[4]
The Impact of Body Mass Index on Abdominal Wall Reconstruction Outcomes: A Comparative Study.

Plast Reconstr Surg. 2017-5

[5]
Impact of obesity on postoperative 30-day outcomes in emergent open ventral hernia repairs.

Am J Surg. 2016-12

[6]
What is the BMI threshold for open ventral hernia repair?

Surg Endosc. 2017-3

[7]
Ventral hernia repair: outcomes change with long-term follow-up.

JSLS. 2012

[8]
Obesity is a risk factor for recurrence after incisional hernia repair.

Hernia. 2004-2

[9]
A comparison of suture repair with mesh repair for incisional hernia.

N Engl J Med. 2000-8-10

[10]
Recurrence after incisional hernia repair: results and risk factors.

Surg Today. 1996

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