Yüksel Yavuz Melike, Coşkun Beyan Ayşe, Ayik Türk Merve, Dizdar Canbaz Türkan, Korkmaz Özgüngör Ö Melis, Şafak Alici Nur
Faculty of Medicine, Pulmonology Department, İzmir Katip Çelebi University, İzmir, Turkey.
Faculty of Medicine, Occupational Medicine Department, Dokuz Eylül University, İzmir, Turkey.
BMC Pulm Med. 2025 May 16;25(1):236. doi: 10.1186/s12890-025-03676-z.
Pneumoconiosis is still the most common occupational disease worldwide. The aim of the study was to evaluate the risk factors affecting survival in patients with pneumoconiosis who were followed up in occupational medicine clinics.
This retrospective descriptive study included all pneumoconiosis patients followed up in occupational medicine clinics between 2013 and 2023. The patients' death records were accessed through the national death notification system.
A total of 539 patients were included in the study. During the clinical follow-up, 14 (2.56%) patients had died. The mean overall survival time was 224 ± 13 months. In multiple analyses, silica exposure (p = 0.029) and lung cancer development (p = 0.002) were associated with survival. There was no difference between stages 0 and 1, stage 2 and stage 3 in terms of age at diagnosis, type of disease and duration of dust exposure (respectively p = 0.109, p = 0.852).
This study showed that exposure to silica as a dust type and the development of lung cancer increased mortality in patients with pneumoconiosis. Determining the factors that may be associated with mortality in patients with pneumoconiosis is important in patient follow-up and in developing preventive measures and policies. It is crucial that the establishment of lung cancer screening programs contribute to life expectancy.
尘肺病仍是全球最常见的职业病。本研究旨在评估在职业医学诊所接受随访的尘肺病患者生存的影响因素。
这项回顾性描述性研究纳入了2013年至2023年间在职业医学诊所接受随访的所有尘肺病患者。通过国家死亡通知系统获取患者的死亡记录。
共有539例患者纳入本研究。在临床随访期间,14例(2.56%)患者死亡。总体生存时间的均值为224±13个月。在多因素分析中,二氧化硅暴露(p = 0.029)和肺癌发生(p = 0.002)与生存相关。0期与1期、2期与3期在诊断年龄、疾病类型和粉尘暴露时长方面无差异(p分别为0.109、0.852)。
本研究表明,作为粉尘类型的二氧化硅暴露和肺癌发生会增加尘肺病患者的死亡率。确定尘肺病患者中可能与死亡率相关的因素对于患者随访以及制定预防措施和政策很重要。肺癌筛查项目的建立有助于延长预期寿命,这一点至关重要。