Ishikawa Yoshinori, Kobayashi Takashi, Abe Eiji, Miyakoshi Naohisa
Department of Orthopedic Surgery, Akita Kousei Medical Center, Akita, Japan.
Johto Orthopedic Clinic, Akita, Japan.
Eur Spine J. 2025 May 17. doi: 10.1007/s00586-025-08925-7.
The impact of immediate postoperative spinal tilt, and the lowest instrumented vertebra (LIV) levels and level fused (LF) even when achieving sufficient spinal restoration, on distal junctional failure (DJF) in adult spinal deformity (ASD) surgery remains unclear. We aimed to understand the risk factors for DJF to decrease revision ASD surgery.
Data from 681 ASD instrumentation surgeries at ≥ 4 levels and ≥ 2 years of follow-up were compared between patients with and without DJF. We evaluated the LF, LIV level, spinal alignment with Scoliosis Research Society (SRS)-Schwab sagittal modifiers (SMs), and clinical outcomes. Multivariable analyses estimated the risk of DJF considering adequate spinal restoration of SMs.
Thirty-five patients required revisions with DJF. Preoperative characteristics were similar between the groups. The DJF group had significantly lower lumbar lordosis (LL) and thoracic kyphosis (TK), the larger sagittal vertical axis (SVA), and T1 pelvic angle (T1PA) immediate postoperatively, and lower SRS-22 pain scores. Furthermore, the DJF group had significantly more L4 and L5 LIVs and fewer S2 alar-iliac fixation (S2AIF). Multivariable analyses after adjusting for factors affecting SMs (SVA and LL) revealed that LIV at L3 (odds ratio [OR] = 11.4), L4 (OR = 6.4), S2AIF (OR = 0.12), and LF (OR = 1.26) was significant.
Immediate postoperative lower LL and TK, larger SVA and T1PA, and lower SRS-22 pain scores may relate to DJF. Moreover, LIV at L3 > L4 > L5>, S2AIF, and high LF may relate to DJF even under sufficient alignment restoration. The LIV and the LF should be carefully selected, even when restoring SMs, to prevent DJF.
即便在实现充分的脊柱复位时,成人脊柱畸形(ASD)手术中术后即刻脊柱倾斜、最低固定椎体(LIV)水平和融合节段(LF)对远端交界性失败(DJF)的影响仍不明确。我们旨在了解DJF的危险因素,以减少ASD翻修手术。
比较了681例接受≥4节段ASD内固定手术且随访≥2年的患者中发生和未发生DJF的患者数据。我们评估了LF、LIV水平、使用脊柱侧弯研究学会(SRS)-施瓦布矢状面修正指标(SMs)评估的脊柱对线情况以及临床结局。多变量分析在考虑SMs充分脊柱复位的情况下估计DJF的风险。
35例患者因DJF需要翻修。两组术前特征相似。DJF组术后即刻腰椎前凸(LL)和胸椎后凸(TK)显著更低,矢状垂直轴(SVA)和T1骨盆角(T1PA)更大,SRS-22疼痛评分更低。此外,DJF组L4和L5作为LIV的情况显著更多,S2翼状髂骨固定(S2AIF)更少。在调整影响SMs的因素(SVA和LL)后进行的多变量分析显示,L3作为LIV(比值比[OR]=11.4)、L4(OR=6.4)、S2AIF(OR=0.12)和LF(OR=1.26)具有显著意义。
术后即刻较低的LL和TK、较大的SVA和T1PA以及较低的SRS-22疼痛评分可能与DJF有关。此外,即便在对线充分恢复的情况下,L3作为LIV>L4作为LIV>L5作为LIV、S2AIF以及较高的LF可能与DJF有关。即使在恢复SMs时,也应谨慎选择LIV和LF,以预防DJF。