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长节段融合术后再次手术:延长脊柱融合至腰椎以下的影响。

Re-operation After Long-Segment Fusions for Adult Spinal Deformity: The Impact of Extending the Construct Below the Lumbar Spine.

机构信息

Department of Neurological Surgery, Rush University Medical Center, Chicago, Illinois.

Division of Neurosurgery, Department of Surgery, University of Toronto, Toronto, Ontario, Canada.

出版信息

Neurosurgery. 2018 Feb 1;82(2):211-219. doi: 10.1093/neuros/nyx163.

Abstract

BACKGROUND

Deciding where to end a long-segment fusion for adult spinal deformity (ASD) may be a challenge, particularly in the absence of an abnormality at L5/S1. Some suggest prophylactic extension of the construct to the sacrum and/or ilium (S/I) to protect against distal junctional failure, while others support terminating in the lower lumbar spine to preserve motion.

OBJECTIVE

To compare the risk of re-operation after long-segment fusions for ASD that ends at L4 or L5 (L4/5) vs S/I.

METHODS

A multicenter database of patients treated for ASD by circumferential minimally invasive surgery or hybrid surgical technique was screened for individuals with long fusions (≥4 vertebral levels) ending at L4 or below and with at least 2 yr of follow-up. Multivariate regression modeling was used to compare surgical morbidity between the L4/5 and S/I groups, and Cox proportional hazard modeling was used to compare risk of re-operation.

RESULTS

There were 45 subjects with fusion to L4/5 and 71 to S/I. Over a 32-mo median follow-up, 41 re-operations were performed; 6 were for distal junctional failure. In those with normal or mild degeneration at L5/S1, fusion to S/I afforded no significant change in re-operative risk (hazard ratio = 1.18 [95% confidence interval: 0.53-2.62], P = .682). In those undergoing circumferential minimally invasive surgery correction, fusion to S/I was associated with significantly greater blood loss (499.6 cc, P < .001) and surgical time (97.5 min, P = .04).

CONCLUSION

In the setting of a normal or mildly degenerated L5/S1 disc space, fusion to the sacrum/ilium did not significantly change the risk of requiring a re-operation after a long-segment fusion for ASD.

摘要

背景

对于成人脊柱畸形(ASD)的长节段融合,确定在何处结束可能是一个挑战,尤其是在 L5/S1 处没有异常的情况下。一些人建议预防性地将构建延伸到骶骨和/或髂骨(S/I)以防止远端交界性失败,而另一些人则支持在较低的腰椎结束以保留运动。

目的

比较 ASD 长节段融合终点位于 L4 或 L5(L4/5)与 S/I 处的再手术风险。

方法

通过环周微创或杂交手术技术治疗 ASD 的多中心数据库中筛选出融合长度≥4 个椎体且随访时间至少 2 年的患者,终点位于 L4 以下,且终点位于 L4/5 或 S/I。采用多变量回归模型比较 L4/5 和 S/I 两组之间的手术发病率,采用 Cox 比例风险模型比较再手术风险。

结果

有 45 例融合至 L4/5,71 例融合至 S/I。在 32 个月的中位随访期间,进行了 41 次再手术;其中 6 例为远端交界性失败。在 L5/S1 处正常或轻度退变的患者中,融合至 S/I 并未显著改变再手术风险(风险比=1.18[95%置信区间:0.53-2.62],P=0.682)。在接受环周微创矫正的患者中,融合至 S/I 与显著更大的出血量(499.6 cc,P<0.001)和手术时间(97.5 min,P=0.04)相关。

结论

在 L5/S1 椎间盘空间正常或轻度退变的情况下,融合至骶骨/髂骨并未显著改变 ASD 长节段融合后需要再手术的风险。

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