Department of Neurological Surgery, Rush University Medical Center, Chicago, Illinois.
Division of Neurosurgery, Department of Surgery, University of Toronto, Toronto, Ontario, Canada.
Neurosurgery. 2018 Feb 1;82(2):211-219. doi: 10.1093/neuros/nyx163.
Deciding where to end a long-segment fusion for adult spinal deformity (ASD) may be a challenge, particularly in the absence of an abnormality at L5/S1. Some suggest prophylactic extension of the construct to the sacrum and/or ilium (S/I) to protect against distal junctional failure, while others support terminating in the lower lumbar spine to preserve motion.
To compare the risk of re-operation after long-segment fusions for ASD that ends at L4 or L5 (L4/5) vs S/I.
A multicenter database of patients treated for ASD by circumferential minimally invasive surgery or hybrid surgical technique was screened for individuals with long fusions (≥4 vertebral levels) ending at L4 or below and with at least 2 yr of follow-up. Multivariate regression modeling was used to compare surgical morbidity between the L4/5 and S/I groups, and Cox proportional hazard modeling was used to compare risk of re-operation.
There were 45 subjects with fusion to L4/5 and 71 to S/I. Over a 32-mo median follow-up, 41 re-operations were performed; 6 were for distal junctional failure. In those with normal or mild degeneration at L5/S1, fusion to S/I afforded no significant change in re-operative risk (hazard ratio = 1.18 [95% confidence interval: 0.53-2.62], P = .682). In those undergoing circumferential minimally invasive surgery correction, fusion to S/I was associated with significantly greater blood loss (499.6 cc, P < .001) and surgical time (97.5 min, P = .04).
In the setting of a normal or mildly degenerated L5/S1 disc space, fusion to the sacrum/ilium did not significantly change the risk of requiring a re-operation after a long-segment fusion for ASD.
对于成人脊柱畸形(ASD)的长节段融合,确定在何处结束可能是一个挑战,尤其是在 L5/S1 处没有异常的情况下。一些人建议预防性地将构建延伸到骶骨和/或髂骨(S/I)以防止远端交界性失败,而另一些人则支持在较低的腰椎结束以保留运动。
比较 ASD 长节段融合终点位于 L4 或 L5(L4/5)与 S/I 处的再手术风险。
通过环周微创或杂交手术技术治疗 ASD 的多中心数据库中筛选出融合长度≥4 个椎体且随访时间至少 2 年的患者,终点位于 L4 以下,且终点位于 L4/5 或 S/I。采用多变量回归模型比较 L4/5 和 S/I 两组之间的手术发病率,采用 Cox 比例风险模型比较再手术风险。
有 45 例融合至 L4/5,71 例融合至 S/I。在 32 个月的中位随访期间,进行了 41 次再手术;其中 6 例为远端交界性失败。在 L5/S1 处正常或轻度退变的患者中,融合至 S/I 并未显著改变再手术风险(风险比=1.18[95%置信区间:0.53-2.62],P=0.682)。在接受环周微创矫正的患者中,融合至 S/I 与显著更大的出血量(499.6 cc,P<0.001)和手术时间(97.5 min,P=0.04)相关。
在 L5/S1 椎间盘空间正常或轻度退变的情况下,融合至骶骨/髂骨并未显著改变 ASD 长节段融合后需要再手术的风险。