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导师指导对ThuFLEP技术围手术期安全性的影响。一项双中心回顾性对照研究。

Impact of mentoring in the perioperative safety of ThuFLEP technique. A two-center retrospective comparative study.

作者信息

Carissimo Hugo, Coscarella Mathieu, Al Barajraji Moncef, Moussa Ilan, Malval Benoit

机构信息

Urology Unit, CHU Ambroise-Paré, Mons, Belgium.

Urology Unit, CHU Ambroise-Paré, Mons, Belgium.

出版信息

Fr J Urol. 2025 Aug;35(6-7):102906. doi: 10.1016/j.fjurol.2025.102906. Epub 2025 May 15.

Abstract

BACKGROUND

Endoscopic enucleation of the prostate (EEP) has become a gold standard for the surgical treatment of symptomatic benign prostatic hyperplasia (BPH). Thulium fiber laser enucleation (ThuFLEP), due to its characteristics, may facilitate quicker and easier adoption for novice surgeons. This study compares the feasibility and the safety of ThuFLEP technique between two novice EEP teams, one with an on-site mentor and one without.

MATERIALS AND METHODS

The study involved 110 patients across two centers. The first, with a mentor (Center M), performed 50 procedures, while the second, without a mentor (Center W), performed 60. The primary endpoint focused on feasibility and perioperative complications. Secondary endpoints included operative efficiency and functional outcomes at three months.

RESULTS

Among post-operative complications, only the transfusion rate differed between the centers (Center M: 4 vs. Center W: 0; P=0.03). Median duration of enucleation and morcellation were respectively 89% longer (P=0.00001) and 75% longer (P=0.00037) in Center W. Enucleation and morcellation efficiencies were respectively 74% (0.87g/min vs. 0.50g/min; P=0.0013) and 42% (3.75g/min vs. 2.62g/min; P=0.0046) lower without a mentor. Three-month functional outcomes were comparable, except for maximum urinary flow, which was higher in the group without a mentor (24.5mL/s vs. 15.5mL/s; P<0.01).

CONCLUSIONS

The acquisition of the ThuFLEP technique by novice surgeons is feasible and safe without a mentor, although having one improves operative time and efficiency.

摘要

背景

前列腺内镜剜除术(EEP)已成为有症状良性前列腺增生(BPH)手术治疗的金标准。由于其特性,铥光纤激光剜除术(ThuFLEP)可能有助于新手外科医生更快、更轻松地采用。本研究比较了两个新手EEP团队(一个有现场指导老师,一个没有)采用ThuFLEP技术的可行性和安全性。

材料与方法

本研究涉及两个中心的110名患者。第一个中心有指导老师(M中心),进行了50例手术,而第二个中心没有指导老师(W中心),进行了60例手术。主要终点集中在可行性和围手术期并发症。次要终点包括手术效率和三个月时的功能结局。

结果

在术后并发症中,只有输血率在两个中心之间存在差异(M中心:4例 vs. W中心:0例;P=0.03)。W中心的剜除和粉碎中位数持续时间分别长89%(P=0.00001)和75%(P=0.00037)。没有指导老师时,剜除和粉碎效率分别低74%(0.87g/分钟 vs. 0.50g/分钟;P=0.0013)和42%(3.75g/分钟 vs. 2.62g/分钟;P=0.0046)。除最大尿流率外,三个月时的功能结局相当,没有指导老师的组最大尿流率更高(24.5mL/秒 vs. 15.5mL/秒;P<0.01)。

结论

新手外科医生在没有指导老师的情况下掌握ThuFLEP技术是可行且安全的,尽管有指导老师可改善手术时间和效率。

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