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一项教育干预对2型糖尿病成年患者代谢综合征各组分的有效性:非随机临床试验

Effectiveness of an educational intervention on the components of the metabolic syndrome of adults with type 2 diabetes: non-randomized clinical trial.

作者信息

Alves de Araújo Wilkslam, Santana Cardoso Santos Isleide, Souza Rosa Randson, Santos Souza Cícero, Pires Cruz Diego, de Oliveira Damaceno Taynnan, Ferreira da Silva Araújo Tiago, Lemos de Azevedo Maia Gabriela, Montargil Rocha Roseanne

机构信息

Nurse, Ph.D., State University of Southwest Bahia (SUSB), Jequié, Bahia, Brazil.

Nurse, Ph.D. student, State University of Feira de Santana (UEFS), Feira de Santana, Bahia, Brazil.

出版信息

Invest Educ Enferm. 2025 Apr;43(1). doi: 10.17533/udea.iee.v43n1e04.

DOI:10.17533/udea.iee.v43n1e04
PMID:40382000
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12085253/
Abstract

OBJECTIVE

To verify the effectiveness of an educational intervention on the components of metabolic syndrome in adults with type 2 diabetes.

METHODS

A non-randomized clinical trial included 51 adults (48.73±7.84 years old; 86.3% women) diagnosed with type 2 diabetes and metabolic syndrome (intervention group, n=26; control group, n=25). The intervention consisted of a multidisciplinary health promotion educational program over six months, structured in seven workshops led by nurses. The primary outcome was the improvement of metabolic syndrome components, and the secondary outcome was the reduction in the number of metabolic syndrome criteria assessed at two time points, baseline and after six months of monitoring.

RESULTS

Compared to the control group, the educational program reduced glucose levels (p=0.001) and improved high-density lipopro-tein cholesterol concentrations (p=0.001) in the intervention group participants at six months. A significant decrease in the mean metabolic syndrome score was observed in the intervention group, while the control group showed an increase (p=0.033). At the end of the study, 11.5% of the participants in the intervention group no longer met the criteria for metabolic syndrome.

CONCLUSION

A nurse-led health promotion educational program was effective in improving glucose and high-density lipoprotein cholesterol levels among adults with type 2 diabetes and metabolic syndrome, as well as reducing the number of metabolic syndrome components in the participants.

摘要

目的

验证一项教育干预措施对2型糖尿病成年患者代谢综合征各组分的有效性。

方法

一项非随机临床试验纳入了51名被诊断为2型糖尿病和代谢综合征的成年人(年龄48.73±7.84岁;女性占86.3%)(干预组,n=26;对照组,n=25)。干预措施包括一项为期6个月的多学科健康促进教育项目,该项目由7个由护士主导的工作坊组成。主要结局是代谢综合征各组分的改善,次要结局是在两个时间点(基线和监测6个月后)评估的代谢综合征标准数量的减少。

结果

与对照组相比,干预组参与者在6个月时,教育项目降低了血糖水平(p=0.001),并改善了高密度脂蛋白胆固醇浓度(p=0.001)。干预组的平均代谢综合征评分显著降低,而对照组则有所升高(p=0.033)。在研究结束时,干预组11.5%的参与者不再符合代谢综合征的标准。

结论

由护士主导的健康促进教育项目对于改善2型糖尿病和代谢综合征成年患者的血糖及高密度脂蛋白胆固醇水平,以及减少参与者的代谢综合征组分数量是有效的。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/76fa/12085253/a06f4924c810/2216-0280-iee-43-01-e04-gf2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/76fa/12085253/15a39082e71e/2216-0280-iee-43-01-e04-gf1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/76fa/12085253/a06f4924c810/2216-0280-iee-43-01-e04-gf2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/76fa/12085253/15a39082e71e/2216-0280-iee-43-01-e04-gf1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/76fa/12085253/a06f4924c810/2216-0280-iee-43-01-e04-gf2.jpg

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本文引用的文献

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A lifestyle intervention with an energy-restricted Mediterranean diet and physical activity enhances HDL function: a substudy of the PREDIMED-Plus randomized controlled trial.能量限制的地中海饮食和身体活动的生活方式干预可增强高密度脂蛋白功能:PREDIMED-Plus 随机对照试验的子研究。
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