Li Wei
Department of Gerontology, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, 200233, China.
Sci Rep. 2025 May 17;15(1):17215. doi: 10.1038/s41598-025-02153-1.
This study investigates the knowledge, attitudes, and practices (KAP) of elderly patients with metabolic associated fatty liver disease (MAFLD). A cross-sectional study was conducted from August to October 2024, involving 404 patients in the Geriatrics Department of Shanghai Sixth People's Hospital. Participants provided demographic information and completed a structured questionnaire to assess KAP scores. A score of ≥ 70% was considered good for knowledge, attitudes, and practices. Structural equation modeling (SEM) was employed to analyze direct and indirect relationships among the KAP dimensions and identify the pathways through which knowledge and attitudes influence practices. The average age of participants was 72.43 ± 7.88 years. Knowledge, attitude, and practice scores were 13.47 ± 5.40, 28.68 ± 5.04, and 28.01 ± 4.61, respectively. SEM findings indicated that knowledge significantly influenced practice (β = 0.39, P < 0.001), and attitudes also notably impacted practice (β = 0.34, P < 0.001), though knowledge's indirect influence through attitudes was not significant (β = 0.03, P = 0.363). Overall, these findings highlight inadequate KAP among elderly patients with MAFLD, exemplified by 75.2% being unfamiliar of MAFLD's progression to cirrhosis or cancer, underscoring the need for targeted educational initiatives to improve self-management and health outcomes.
本研究调查了老年代谢相关脂肪性肝病（MAFLD）患者的知识、态度和行为（KAP）。2024年8月至10月进行了一项横断面研究，纳入了上海第六人民医院老年医学科的404名患者。参与者提供了人口统计学信息，并完成了一份结构化问卷以评估KAP得分。知识、态度和行为得分≥70%被认为良好。采用结构方程模型（SEM）分析KAP维度之间的直接和间接关系，并确定知识和态度影响行为的途径。参与者的平均年龄为72.43±7.88岁。知识、态度和行为得分分别为13.47±5.40、28.68±5.04和28.01±4.61。SEM结果表明，知识显著影响行为（β=0.39，P<0.001），态度也显著影响行为（β=0.34，P<0.001），尽管知识通过态度的间接影响不显著（β=0.03，P=0.363）。总体而言，这些发现突出了老年MAFLD患者KAP不足的情况，例如75.2%的患者不了解MAFLD进展为肝硬化或癌症的情况，强调了需要有针对性的教育举措来改善自我管理和健康结果。
