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母亲激励健康行动(MIHA)项目:一项针对母女二人组肥胖治疗的随机对照试验。

Mothers Inspiring Healthy Actions (MIHA) program: A randomized control trial testing obesity treatment for mother-daughter dyads.

作者信息

Marquez Becky, Zhang Xinlian, Lebensohn-Chialvo Florencia, Butte Katie Thralls, Arredondo Elva, Allison Matthew

机构信息

Herbert Wertheim School of Public Health & Human Longevity Science, University of California San Diego, La Jolla, CA, United States of America.

Herbert Wertheim School of Public Health & Human Longevity Science, University of California San Diego, La Jolla, CA, United States of America.

出版信息

Contemp Clin Trials. 2025 Jul;154:107946. doi: 10.1016/j.cct.2025.107946. Epub 2025 May 16.

Abstract

BACKGROUND

Obesity and diabetes are highly concordant in Mexican American families. From a family systems perspective, family-level approaches to obesity treatment can improve the adoption and maintenance of weight management behaviors. Hence, this study will conduct a randomized control trial testing the efficacy of an adapted behavioral weight management intervention with counseling on family functioning.

METHODS

Mexican American mothers and adult daughters will be randomly assigned to receive behavioral obesity treatment with (BTR) or without (BT) relationship skills training. Dyads participating in BTR and BT will attend 24 weekly sessions focused on nutrition and physical activity education along with cognitive and behavioral change strategies. Dyads participating in BTR will also receive experiential-based relationship skills training to address culturally influenced relational dynamics that may interfere with dyadic collaboration for lifestyle change. The 12-month trial will consist of an intervention phase (1-6 months) and a maintenance phase (7-12 months). The primary outcome is weight loss. Secondary outcomes include treatment adherence, cardiometabolic risk factors, health behaviors, psychosocial factors, and family functioning.

CONCLUSION

Dyads in the BTR group are expected to achieve greater improvements in primary and secondary outcomes than the BT group.

摘要

背景

肥胖症和糖尿病在墨西哥裔美国家庭中高度相关。从家庭系统的角度来看,家庭层面的肥胖症治疗方法可以提高体重管理行为的采用率和维持率。因此,本研究将进行一项随机对照试验,测试一种经过调整的行为体重管理干预措施结合家庭功能咨询的效果。

方法

墨西哥裔美国母亲和成年女儿将被随机分配接受有(BTR)或无(BT)关系技能培训的行为性肥胖症治疗。参与BTR和BT的二人组将参加24次每周一次的课程,重点是营养和体育活动教育以及认知和行为改变策略。参与BTR的二人组还将接受基于体验的关系技能培训,以解决可能干扰生活方式改变的二元合作的文化影响的关系动态问题。为期12个月的试验将包括一个干预阶段(1 - 6个月)和一个维持阶段(7 - 12个月)。主要结果是体重减轻。次要结果包括治疗依从性、心脏代谢危险因素、健康行为、心理社会因素和家庭功能。

结论

预计BTR组的二人组在主要和次要结果方面比BT组有更大的改善。

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