Aksoy Kemal, Deniz Abdülkerim, Metin Mert, Insel Mahmut, Pekmezci Aytaç
Depertmant of Internal Medicine, Milas, Muğla Sitki Kocman University, Muğla, Turkey.
Free Researcher for Clinical Biochemistry, Nisbetiye Mah. Bakır Sok. Beşiktaş, Istanbul, Turkey.
J Vet Intern Med. 2025 May-Jun;39(3):e70122. doi: 10.1111/jvim.70122.
The incidence of subclinical hypocalcemia (iSCH) based on blood ionized calcium (iCa < 1.00 mmol/L) has not been investigated in Holsteins fed an anionic diet (AD) and non-AD prepartum and treated or not treated with calcium bolus (CB) around the time of calving.
Anionic diets supported with CB at 12 h after calving should increase iCa and reduce iSCH better than AD + non-CB and non-AD + CB.
One hundred Holsteins were allocated to 4 groups: Group 1 (AD + CB), group 2 (AD + non-CB), group 3 (non-AD + CB) and group 4 (non-AD and non-CB).
The animals were randomly selected according to calving order. The iCa and iSCH were analyzed at calving before CB application on postpartum days (PPD) 1, 3, and 10. Urine pH was analyzed at calving and PPD1.
Urine pH (6.43 ± 0.26), iCa (0.90 ± 0.16 mmol/L) and iSCH (50%) were significantly different in the combined AD groups compared to the non-AD groups at calving. Multiparous cows in combined AD groups had higher iCa and lower iSCH at calving. Group 1 had a higher iCa than groups 3 and 4. Group 2 had a higher iCa than Group 4 at PPD3. The iSCH of group 1 at PPD3 and 10 was lower than that of other groups. The iSCH decreased from 50% (PPD1) to 17% (PPD3) and 4% (PPD10) in group 1. Group 4 showed milk fever of 12%, 4%, and 4% at PPD1, 3, and 9, respectively.
Group 1 was the most appropriate protocol to increase iCa, reduce iSCH, and prevent milk fever.
尚未对产前饲喂阴离子日粮（AD）和非阴离子日粮且产犊前后接受或未接受钙丸（CB）处理的荷斯坦奶牛进行基于血离子钙（iCa<1.00 mmol/L）的亚临床低钙血症（iSCH）发病率的研究。
产犊后12小时给予CB支持的阴离子日粮应比AD+非CB和非AD+CB组能更好地提高iCa并降低iSCH。
100头荷斯坦奶牛被分为4组：第1组（AD+CB）、第2组（AD+非CB）、第3组（非AD+CB）和第4组（非AD且非CB）。
根据产犊顺序随机选择动物。在产后第1、3和10天产犊时应用CB之前分析iCa和iSCH。在产犊时和产后第1天分析尿液pH值。
与产犊时的非AD组相比，联合AD组的尿液pH值（6.43±0.26）、iCa（0.90±0.16 mmol/L）和iSCH（50%）有显著差异。联合AD组的经产奶牛在产犊时有较高的iCa和较低的iSCH。第1组的iCa高于第3组和第4组。产后第3天，第2组的iCa高于第4组。第1组在产后第3天和第10天的iSCH低于其他组。第1组的iSCH从产后第1天的50%降至产后第3天的17%和产后第10天的4%。第4组在产后第1、3和9天分别出现12%、4%和4%的产乳热。
第1组是提高iCa、降低iSCH和预防产乳热的最合适方案。
