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使用垂直可扩展人工钛肋(VEPTR)对先天性早发性脊柱侧弯进行手术治疗:病例系列

Operative management of congenital early-onset scoliosis using the vertical expandable prosthetic titanium rib (VEPTR): a case series.

作者信息

Mohammed Riaz, Shah Pranav, Jones Alwyn, Ahuja Sashin, Howes John

机构信息

Spine Surgery, University Hospital of Wales, Cardiff, UK.

Gloucestershire Hospitals NHS Foundation Trust, Cheltenham, England, UK.

出版信息

World J Pediatr Surg. 2025 May 13;8(2):e000972. doi: 10.1136/wjps-2024-000972. eCollection 2025.

Abstract

To analyze surgical challenges and outcomes in patients who completed the whole journey of vertical expandable prosthetic titanium rib (VEPTR) treatment for congenital early-onset scoliosis (C-EOS), given the limited evidence available on VEPTR graduates. A retrospective review was conducted on nine consecutive patients with C-EOS and thoracic hypoplasia treated at a single tertiary care center, with assessment of clinical and radiological outcomes. At mean duration of 7.4 (range 4.3-10.5) years of VEPTR treatment, the mean coronal deformity angle measured 65° preoperatively, 50° postoperatively, and 58° at final follow-up. Mean T1-S1 length (pre-op 252 mm, final follow-up 333 mm) and T1-T12 length (preop 128 mm, final follow-up 196 mm) improved by 32% at final follow-up. Mean space available for lung was 86% (range 79%-93%) preoperatively, increasing to 90% (range 85%-95%) postoperatively and 97% (range 87%-107%) at final follow-up. Nine children had a cumulative 17 (188%) complications comprising wound problems, infection, and device migration or prominence. In five patients who underwent definitive fusion, mean coronal deformity angle and T1-S1 length improved by 17% and 11%, respectively. VEPTR is valuable in managing EOS, particularly in patients with thoracic insufficiency syndrome. However, the need for multiple surgeries, limited correction potential, and risk of partial loss of correction make it less suitable for other cases.

摘要

鉴于关于垂直可扩展人工钛肋骨(VEPTR)治疗先天性早发性脊柱侧凸(C-EOS)全程治疗患者的手术挑战和结果的证据有限,对其进行分析。对在单一三级医疗中心接受治疗的9例连续的C-EOS和胸廓发育不全患者进行回顾性研究,评估临床和放射学结果。在VEPTR治疗的平均7.4年(范围4.3 - 10.5年)时,术前平均冠状面畸形角度为65°,术后为50°,末次随访时为58°。末次随访时,平均T1-S1长度(术前252 mm,末次随访333 mm)和T1-T12长度(术前128 mm,末次随访196 mm)改善了32%。术前肺可用空间平均为86%(范围79% - 93%),术后增加到90%(范围85% - 95%),末次随访时为97%(范围87% - 107%)。9名儿童共发生17例(188%)并发症,包括伤口问题、感染以及器械移位或突出。在5例接受确定性融合手术的患者中,平均冠状面畸形角度和T1-S1长度分别改善了17%和11%。VEPTR在治疗EOS方面具有价值,特别是对于胸廓功能不全综合征患者。然而,需要多次手术、有限的矫正潜力以及部分矫正丢失的风险使其不太适合其他病例。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/15cb/12083380/58ca9d8e3960/wjps-8-2-g001.jpg

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