Haouzi Alice, Khayata Mohamed, Jaber Wael A, Xu Bo
Robert and Suzanne Tomsich Department of Cardiovascular Medicine, Sydell and Arnold Family Heart, Vascular, and Thoracic Institute, Cleveland Clinic, Cleveland, OH, USA.
Section of Cardiovascular Imaging, Robert and Suzanne Tomsich Department of Cardiovascular Medicine, Sydell and Arnold Family Heart, Vascular, and Thoracic Institute, Cleveland Clinic, Cleveland, OH, USA.
Cardiovasc Diagn Ther. 2025 Apr 30;15(2):465-479. doi: 10.21037/cdt-2024-605. Epub 2025 Apr 23.
Recent major international society guidelines have highlighted the utility of multi-modality imaging in the evaluation of infective endocarditis (IE). This article aims to discuss the contemporary applications of multimodality imaging in IE through real-life cases, demonstrating how emerging imaging modalities, including cardiac computed tomography (CCT) and nuclear imaging techniques can be used.
A literature search of the PubMed database was performed between Jan 01, 2024 and Oct 01, 2024. Relevant articles on the subjects of "infective endocarditis" and "multi-modality imaging" were used in our review. Four clinical cases from the Cleveland Clinic Foundation were incorporated to supplement this literature review with real-world examples.
This literature review encompasses international cardiology guidelines, as well as investigational studies, meta-analyses, and dedicated reviews highlighting the specific roles, strengths, and weaknesses of different imaging modalities in the evaluation of IE, including transthoracic and transesophageal echocardiography (TEE), CCT, F-fluorodeoxyglucose positron emission tomography (F-FDG PET), and white blood cell single-photon emission computed tomography (WBC SPECT). This review demonstrates the emerging role for these multi-modality imaging tools in light of an increasingly complex patient population with growing numbers of prosthetic valves and devices.
The current literature and guidelines are discussed with reference to complex clinical cases, with the aim of illustrating the relative advantages and disadvantages, and appropriate utility of multimodality cardiac imaging in IE.
近期主要国际学会指南强调了多模态成像在感染性心内膜炎（IE）评估中的作用。本文旨在通过实际病例讨论多模态成像在IE中的当代应用，展示包括心脏计算机断层扫描（CCT）和核成像技术在内的新兴成像模态如何得以应用。
于2024年1月1日至2024年10月1日期间在PubMed数据库进行文献检索。我们的综述使用了关于“感染性心内膜炎”和“多模态成像”主题的相关文章。纳入了克利夫兰诊所基金会的4个临床病例，用实际例子补充这篇文献综述。
这篇文献综述涵盖了国际心脏病学指南，以及调查研究、荟萃分析和专门综述，突出了不同成像模态在IE评估中的具体作用、优势和劣势，包括经胸和经食管超声心动图（TEE）、CCT、F-氟脱氧葡萄糖正电子发射断层扫描（F-FDG PET）和白细胞单光子发射计算机断层扫描（WBC SPECT）。鉴于患者群体日益复杂，人工瓣膜和器械数量不断增加，本综述展示了这些多模态成像工具的新兴作用。
结合复杂临床病例对当前文献和指南进行了讨论，目的是阐明多模态心脏成像在IE中的相对优缺点及适当用途。
