Ramírez-García Daniel, Perezalonso-Espinosa Jerónimo, Méndez-Labra Padme Nailea, Fermín-Martínez Carlos A, Díaz-Sánchez Juan Pablo, Paz-Cabrera César Daniel, Vargas-Vázquez Arsenio, López-Teros Miriam Teresa, Flood David, Manne-Goehler Jennifer, Antonio-Villa Neftali Eduardo, Danaei Goodarz, Seiglie Jacqueline A, Bello-Chavolla Omar Yaxmehen
Research Division, Instituto Nacional de Geriatría, Mexico City, Mexico.
Facultad de Medicina, Universidad Nacional Autónoma de México, Mexico City, Mexico.
medRxiv. 2025 May 5:2024.09.18.24313926. doi: 10.1101/2024.09.18.24313926.
Effective cardiovascular disease (CVD) risk management is a cornerstone of optimal diabetes care. Here, we estimated the prevalence and determinants of CVD risk factor control amongst individuals with diagnosed diabetes in Mexico.
We analyzed data from individuals with diagnosed diabetes ≥20 years from the 2016-2023 Mexican National Health and Nutrition Surveys. We estimated the prevalence of glycemic, blood pressure (BP), non-current smoking, and combined CVD risk factor control. LDL-C control was assessed using SCORE2-Diabetes risk categories. We estimated the prevalence of BP-lowering, cholesterol-lowering, and glucose-lowering medication use, and explored determinants of control achievement using logistic regression.
We analyzed data representing 43.2 million adults with diagnosed diabetes during 2016-2023. In 2023, glycemic control was 29% (95%CI 21%-38%), BP control 22.9% (95%CI 14%-31%), and non-current smoking 89% (95%CI 81%-96%). The proportion of people classified as high or very-high CVD risk increased from 59.8% (95%CI 52.1%-67.0%) in 2016 to 68.4% (95%CI 55.6%-78.9%) in 2023, representing ~5.1 million adults. LDL-C control prevalence increased from 2.8% (95%CI 1.2%-4.4%) in 2016 to 6.6% (95%CI 1.9%-11.2%) in 2023. Combined risk factor control achievement was low primarily due to suboptimal LDL-C control, despite high medication use; this was more likely achieved in females, younger individuals, and those with college education or living in states with higher socioeconomic position.
Despite increasing CVD risk during this period, comprehensive glycemic and CVD risk factor management for adults with diabetes in Mexico remains suboptimal. Our findings highlight the need for strategies to address gaps in CVD risk management to reduce premature mortality in this population.
有效的心血管疾病(CVD)风险管理是优化糖尿病护理的基石。在此,我们估计了墨西哥已确诊糖尿病患者中CVD危险因素控制的患病率及决定因素。
我们分析了2016 - 2023年墨西哥国家健康与营养调查中年龄≥20岁的已确诊糖尿病患者的数据。我们估计了血糖、血压(BP)、非当前吸烟及综合CVD危险因素控制的患病率。使用SCORE2 - 糖尿病风险类别评估低密度脂蛋白胆固醇(LDL - C)控制情况。我们估计了使用降压、降胆固醇和降糖药物的患病率,并使用逻辑回归探索控制达标情况的决定因素。
我们分析了代表2016 - 2023年期间4320万已确诊糖尿病成年人的数据。2023年,血糖控制率为29%(95%置信区间21% - 38%),血压控制率为22.9%(95%置信区间14% - 31%),非当前吸烟率为89%(95%置信区间81% - 96%)。被归类为高或非常高CVD风险的人群比例从2016年的59.8%(95%置信区间52.1% - 67.0%)增至2023年的68.4%(95%置信区间55.6% - 78.9%),相当于约510万成年人。LDL - C控制患病率从2016年的2.8%(95%置信区间1.2% - 4.4%)增至2023年的6.6%(95%置信区间1.9% - 11.2%)。尽管药物使用率高,但综合危险因素控制达标率低,主要原因是LDL - C控制不理想;女性、年轻人以及受过大学教育或生活在社会经济地位较高州的人更有可能实现控制达标。
尽管在此期间CVD风险增加,但墨西哥糖尿病成年人的综合血糖和CVD危险因素管理仍不理想。我们的研究结果凸显了制定策略以弥补CVD风险管理差距从而降低该人群过早死亡率的必要性。