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一名53岁男性因登革热引发完全性心脏传导阻滞(心脏型登革热)需植入永久性起搏器:病例报告

Dengue Fever-Induced Complete Heart Block (Cardiac Dengue) Requiring Permanent Pacemaker Implantation in a 53-Year-Old Man: A Case Report.

作者信息

Alnuaimi Maitha K

机构信息

Internal Medicine, Tawam Hospital, Abu Dhabi, ARE.

出版信息

Cureus. 2025 Apr 16;17(4):e82372. doi: 10.7759/cureus.82372. eCollection 2025 Apr.

DOI:10.7759/cureus.82372
PMID:40385752
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12083512/
Abstract

Dengue fever is an endemic mosquito-borne viral infection in many tropical and subtropical regions. While its common manifestations include high-grade fever, rash, and myalgia, cardiac complications, particularly complete heart block, are rare but potentially life-threatening, underscoring the importance of vigilance. A 53-year-old man with type 2 diabetes mellitus and hypertension presented with dizziness, weakness, and a five-day history of high-grade fever with chills. He lived in a dengue-endemic area and denied any recent travel. Physical examination revealed bradyarrhythmia (38-49 beats per minute) and hypotension (99/72 millimeters of mercury). Laboratory tests confirmed acute dengue infection. Despite supportive care and temporary pacing, the patient's intrinsic atrioventricular conduction showed no recovery, leading to persistent pacemaker dependence. On hospital day 17, a permanent dual-chamber pacemaker was implanted. He stabilized after the procedure and was discharged with close follow-up. The diagnosis of dengue was established using standard clinical criteria, confirmed by serologies for immunoglobulin M and immunoglobulin G and reverse transcription polymerase chain reaction. Comprehensive investigations excluded other bradyarrhythmia causes, such as Lyme disease, sarcoidosis, and myocarditis, supporting dengue as the sole etiology. This case highlights the rare but significant phenomenon of dengue-induced complete heart block, emphasizing that long-term pacemaker support may be necessary if conduction fails to recover. By adding to the limited data on dengue-associated advanced conduction disturbances, this case underscores the need for early recognition and multidisciplinary management to improve outcomes.

摘要

登革热是许多热带和亚热带地区流行的一种由蚊子传播的病毒感染。其常见表现包括高热、皮疹和肌痛,心脏并发症,尤其是完全性心脏传导阻滞,虽然罕见但可能危及生命,这凸显了警惕的重要性。一名患有2型糖尿病和高血压的53岁男性出现头晕、乏力,并有5天高热伴寒战的病史。他居住在登革热流行地区,否认近期有旅行史。体格检查发现心动过缓(每分钟38 - 49次)和低血压(99/72毫米汞柱)。实验室检查确诊为急性登革热感染。尽管给予了支持治疗和临时起搏,但患者的固有房室传导未恢复,导致持续依赖起搏器。在住院第17天,植入了永久性双腔起搏器。术后他病情稳定,出院后进行密切随访。登革热的诊断采用标准临床标准,并通过免疫球蛋白M和免疫球蛋白G的血清学检查以及逆转录聚合酶链反应得以证实。全面检查排除了其他导致心动过缓的原因,如莱姆病、结节病和心肌炎,支持登革热为唯一病因。该病例突出了登革热诱发完全性心脏传导阻滞这一罕见但重要的现象,强调如果传导未能恢复,可能需要长期起搏器支持。通过补充关于登革热相关严重传导障碍的有限数据,该病例强调了早期识别和多学科管理以改善预后的必要性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1362/12083512/8f4b7e64d539/cureus-0017-00000082372-i06.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1362/12083512/cc3035bfdbfe/cureus-0017-00000082372-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1362/12083512/14165877757d/cureus-0017-00000082372-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1362/12083512/d8a0b06d30d9/cureus-0017-00000082372-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1362/12083512/deca340d59f1/cureus-0017-00000082372-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1362/12083512/2431805d6388/cureus-0017-00000082372-i05.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1362/12083512/8f4b7e64d539/cureus-0017-00000082372-i06.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1362/12083512/cc3035bfdbfe/cureus-0017-00000082372-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1362/12083512/14165877757d/cureus-0017-00000082372-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1362/12083512/d8a0b06d30d9/cureus-0017-00000082372-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1362/12083512/deca340d59f1/cureus-0017-00000082372-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1362/12083512/2431805d6388/cureus-0017-00000082372-i05.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1362/12083512/8f4b7e64d539/cureus-0017-00000082372-i06.jpg

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