Suzuki Shintaro, Kuroda Hiromitsu, Nagano Nobutaka, Nishikawa Ryo, Edanaga Mitsutaka, Tatsumi Hiroomi, Kazuma Satoshi
Department of Intensive Care Medicine, Sapporo Medical University, School of Medicine, Sapporo, JPN.
Department of Cardiovascular, Renal and Metabolic Medicine, Sapporo Medical University, School of Medicine, Sapporo, JPN.
Cureus. 2025 Apr 18;17(4):e82518. doi: 10.7759/cureus.82518. eCollection 2025 Apr.
Post-anesthetic shivering (PAS) is common after general anesthesia and causes sympathetic excitement, followed by elevated blood pressure. Mitral valve transcatheter edge-to-edge repair (TEER) with MitraClip® (Abbott, Santa Clara, CA) increases left ventricular output resistance because of mitral valve narrowing. PAS after TEER synergistically raises cardiac load, surpassing the left ventricular working reserve and greatly increasing the risk of left ventricular failure in patients. A 64-year-old woman diagnosed with functional severe mitral regurgitation underwent implantation of MitraClip under general anesthesia and was subsequently transferred to the intensive care unit (ICU). Thirty minutes after admission to the ICU, the patient exhibited shivering, elevated blood pressure, and reduced oxygen saturation. There was no evidence of clip displacement, and the cause of this oxygenation impairment was considered to be hypertensive heart failure triggered by shivering. Noninvasive mechanical ventilation, antihypertensive medication, and body surface warming were initiated. The patient showed signs of recovery within two hours. Shivering can increase patient risk after TEER. Effective prevention of shivering is essential because TEER, along with shivering, can increase left ventricular ejection resistance, known as afterload mismatch.
麻醉后寒战(PAS)在全身麻醉后很常见,会引起交感神经兴奋,继而导致血压升高。使用MitraClip®(雅培公司,加利福尼亚州圣克拉拉)进行二尖瓣经导管缘对缘修复(TEER)会因二尖瓣狭窄而增加左心室输出阻力。TEER后的PAS会协同增加心脏负荷,超过左心室的工作储备,大大增加患者发生左心室衰竭的风险。一名64岁被诊断为功能性严重二尖瓣反流的女性在全身麻醉下接受了MitraClip植入,随后被转入重症监护病房(ICU)。入住ICU 30分钟后,患者出现寒战、血压升高和血氧饱和度降低。没有夹子移位的迹象,这种氧合障碍的原因被认为是寒战引发的高血压性心力衰竭。于是开始进行无创机械通气、抗高血压药物治疗和体表保暖。患者在两小时内显示出恢复迹象。寒战会增加TEER术后患者的风险。有效预防寒战至关重要,因为TEER与寒战一起会增加左心室射血阻力,即后负荷不匹配。