Phillips Justin, Kabolowsky Max, Hendon Alex M, Arzillo Samantha
HCA Florida Westside Hospital, Plantation, Florida.
Mount Sinai Medical Center, Aventura, Florida.
HCA Healthc J Med. 2025 Apr 1;6(2):177-181. doi: 10.36518/2689-0216.1857. eCollection 2025.
With the advent of catheter guided interventions, practitioners have added another tool alongside chemical lysis and surgical removal to reduce the clot burden of patients with large emboli and thrombi. Due to comorbid conditions, many patients are poor candidates for surgical or chemical clot treatment but may present optimally for catheter-based thromboembolectomy. In this case, we highlight the benefits of mechanical thrombectomy with transesophageal echocardiographic guidance to reduce the clot burden of a patient who would otherwise be considered a poor candidate for surgical or chemical treatment.
This case follows a 78-year-old man with a past medical history significant for persistent atrial fibrillation, type 2 diabetes, hypertension, hyperlipidemia, coronary artery disease, cardiomyopathy status post biventricular implantable cardioverter-defibrillator, left atrial appendage exclusion device, and a recent deep vein thrombosis. The patient was taking apixaban and was found to have a large, mobile, right atrial thrombus on a transthoracic echocardiograpic evaluation for a routine sepsis workup. The patient underwent an emergency thrombectomy due to the high risk of thrombus embolization. Due to the large size of the thrombus and complexity of the case, an intra-operative inferior vena cava filter was placed to prevent shower embolization of the thrombus during evacuation. Under guidance from the transesophageal echocardiography, the thrombus was successfully removed using a mechanical thrombectomy device.
In an aging population with significant cardiac or hematological comorbidities, some patients who develop right atrial thrombi may be considered poor candidates for an open thrombectomy or chemical thrombolysis. With the development of catheter based mechanical thrombectomy interventions, patients with relative contraindications to traditional methods may benefit from newer technology, especially if the technique allows for accurate visualization of the thrombus via transesophageal echocardiography.
随着导管引导介入技术的出现,从业者在化学溶栓和手术清除之外又增加了一种工具,以减轻患有大栓子和血栓患者的血栓负荷。由于合并症,许多患者并非手术或化学血栓治疗的理想人选,但可能是基于导管的血栓切除术的最佳适用对象。在此病例中,我们强调经食管超声心动图引导下机械血栓切除术的益处,以减轻一名原本被认为不适合手术或化学治疗的患者的血栓负荷。
该病例为一名78岁男性,既往病史包括持续性房颤、2型糖尿病、高血压、高脂血症、冠状动脉疾病、双心室植入式心脏复律除颤器植入术后心肌病、左心耳封堵装置以及近期深静脉血栓形成。患者正在服用阿哌沙班,在因常规脓毒症检查进行经胸超声心动图评估时发现有一个大的、可移动的右心房血栓。由于血栓栓塞风险高,患者接受了紧急血栓切除术。由于血栓体积大且病例复杂,术中放置了下腔静脉滤器,以防止在清除血栓过程中血栓发生淋浴样栓塞。在经食管超声心动图引导下,使用机械血栓切除装置成功清除了血栓。
在患有严重心脏或血液系统合并症的老年人群中,一些发生右心房血栓的患者可能被认为不适合进行开放性血栓切除术或化学溶栓。随着基于导管的机械血栓切除干预技术的发展,对传统方法有相对禁忌证的患者可能会从新技术中受益,特别是如果该技术能够通过经食管超声心动图准确显示血栓。