Alsobyani Faris, Almalki Mansour, Rokbah Hassan Abu
General Surgery Department, Al Noor Specialist Hospital, 3rd Ring Rd, 24241, Makkah, Saudi Arabia.
J Surg Case Rep. 2025 May 17;2025(5):rjaf307. doi: 10.1093/jscr/rjaf307. eCollection 2025 May.
Well-differentiated neuroendocrine tumors (NETs) of the ileocecal region are rare but increasingly recognized gastrointestinal neoplasms. They often present vague symptoms, delaying diagnosis. Despite slow growth, these tumors can metastasize to the liver and bone, complicating management. Despite their indolent nature, these tumors can metastasize to the liver and bone, complicating treatment. We report a case of a 54-year-old woman with a one-year history of vague abdominal symptoms that worsened over the last 2 months. Contrast-enhanced computed tomography imaging revealed a mesenteric lesion leading to partial intestinal obstruction. Further imaging revealed liver and spine metastases. Colonoscopy confirmed an obstructing ileocecal mass, and biopsy identified a Grade 1 well-differentiated NET. The patient underwent laparoscopic right hemicolectomy with ileocolic anastomosis for symptom relief, followed by octreotide therapy. This case highlights the diagnostic and therapeutic challenges of metastatic ileocecal NETs and emphasizes the importance of a multidisciplinary approach for effective treatment and long-term stability.
回盲部高分化神经内分泌肿瘤(NETs)虽罕见,但却是日益受到认可的胃肠道肿瘤。它们常表现出模糊的症状,从而延误诊断。尽管生长缓慢,但这些肿瘤可转移至肝脏和骨骼,使治疗复杂化。尽管其性质惰性,但这些肿瘤仍可转移至肝脏和骨骼,使治疗变得复杂。我们报告一例54岁女性,有一年腹部模糊症状史,在过去2个月内症状加重。增强计算机断层扫描成像显示肠系膜病变导致部分肠梗阻。进一步成像显示有肝脏和脊柱转移。结肠镜检查证实回盲部有阻塞性肿块,活检确定为1级高分化NET。患者接受了腹腔镜右半结肠切除术及回结肠吻合术以缓解症状,随后接受奥曲肽治疗。该病例突出了转移性回盲部NETs的诊断和治疗挑战,并强调了多学科方法对有效治疗和长期稳定的重要性。