Gómez Sánchez Alicia, Tordable Ojeda Cristina, Proaño Landázuri Sara Monserrat, Cabezalí Barbacho Daniel, Gómez Fraile Andrés
Department of Pediatric Surgery, Hospital Universitario 12 de Octubre, Madrid, Spain.
Int Urol Nephrol. 2025 May 19. doi: 10.1007/s11255-025-04558-3.
In the pediatric population, lower urinary tract dysfunction, usually, is due to neurogenic or anatomic defects. In this context, when conservative treatment fails, augmentation enterocystoplasty is a treatment option with good functional results. Nevertheless, multiple complications have been associated with this technique.
We conducted a retrospective review of the patients who underwent bladder augmentation surgery at our hospital over the past 25 years. Statistical analyses were performed to identify potential factors associated with the occurrence of complications.
A total of 34 patients underwent augmentation enterocystoplasty during the study period. A total of 90 complications were recorded in 30 patients (88.2%). The average number of complications per patient was 2.6 ± 1.9. Reintervention was required in 28 patients (82.4%) due to complications, with a mean of 2.29 reoperations per patient. The most frequent complication was lithiasis (17/90), followed by stoma-related issues in the catheterizable duct (14/90), and urinary tract infections (10/90). Patients with exstrophy (p = 0.0028, IRR 3.4, 95% CI 1.71-6.78), bladder neck surgery (p = 0.014, IRR 2.04, 95% CI 1.29-3.21), and catheterizable duct (p = 0.002, IRR 2.56, 95% CI 1.61-4.06) had a significantly higher number of complications.
In our study, over 85% of patients who underwent bladder augmentation surgery experienced at least one complication during follow-up. The risk was significantly higher in patients with bladder exstrophy and in those who had a bladder neck procedure.
在儿科人群中,下尿路功能障碍通常是由神经源性或解剖学缺陷引起的。在这种情况下,当保守治疗失败时,扩大性膀胱成形术是一种功能效果良好的治疗选择。然而,该技术已出现多种并发症。
我们对我院过去25年中接受膀胱扩大手术的患者进行了回顾性研究。进行统计分析以确定与并发症发生相关的潜在因素。
在研究期间,共有34例患者接受了扩大性膀胱成形术。30例患者(88.2%)共记录到90例并发症。每位患者的平均并发症数为2.6±1.9。28例患者(82.4%)因并发症需要再次干预,每位患者平均再次手术2.29次。最常见的并发症是结石(17/90),其次是可控性导尿管道的造口相关问题(14/90)和尿路感染(10/90)。膀胱外翻患者(p = 0.0028,发病率比值比3.4,95%可信区间1.71 - 6.78)、膀胱颈手术患者(p = 0.014,发病率比值比2.04,95%可信区间1.29 - 3.21)和可控性导尿管道患者(p = 0.002,发病率比值比2.56,95%可信区间1.61 - 4.06)的并发症数量显著更高。
在我们的研究中,超过85%接受膀胱扩大手术的患者在随访期间至少经历了一种并发症。膀胱外翻患者和接受膀胱颈手术的患者的风险显著更高。