Alves Arthur Antônio Freire, Vasconcelos Arthur Felipe Barbosa, de Sá Carvalho Francisco Anderson, Pessoa Filho Gilmar Leite, Gomes Ana Luísa Castelo Branco, Nepomuceno Adriana M T, Leite Juliana Magalhães, de Souza Andrade Rafael, Barros João Alfredo M M, Meira Alex Tiburtino
Departamento de Medicina Interna, Serviço de Neurologia, Universidade Federal da Paraíba, Campus I, Jardim Universitário, S/N, Castelo Branco, João Pessoa, PB, 58051-900, Brazil.
Serviço de Neurologia, Hospital Metropolitano Dom José Maria Pires, João Pessoa, PB, Brazil.
Cerebellum. 2025 May 19;24(4):101. doi: 10.1007/s12311-025-01855-6.
In this case report, we describe a male patient, aged 65 years, with previous arterial hypertension and atrial fibrillation, with irregular use of losartan, presenting with sudden onset of dizziness, dysarthria, and bilateral ataxia, 5.5 h before the admission to the neurological emergency department. The cranial magnetic resonance imaging revealed hyperintensities on T2/FLAIR sequences, and diffusion restriction in the territory irrigated by both superior cerebellar arteries, alongside with left pontine, compatible with infarct. The CT angiography of the cervical and cerebral arteries revealed a thromboembolic occlusion of the top of the basilar artery. Furthermore, atrial fibrillation was confirmed based on the results of the electrocardiogram. During hospitalization, the patient was treated with metoprolol and dabigatran. Upon discharge, the patient demonstrated a partial improvement in symptoms under medication and was scheduled to return to the outpatient clinic after 30 days. Our case highlights the importance of considering ischemic stroke in the territory of the cerebellar superior artery bilaterally, due to a top of basilar thrombus, in patients presenting with global cerebellar ataxia, with no consciousness or visual alteration. Clinical Trial Number Not applicable.
在本病例报告中,我们描述了一名65岁男性患者,既往有动脉高血压和心房颤动病史,不规律使用氯沙坦,在入住神经科急诊室前5.5小时突然出现头晕、构音障碍和双侧共济失调。头颅磁共振成像显示T2/FLAIR序列上有高信号,双侧小脑上动脉供血区域有弥散受限,同时左侧脑桥也有异常,符合梗死表现。颈部和脑血管CT血管造影显示基底动脉顶端血栓栓塞性闭塞。此外,根据心电图结果确诊为心房颤动。住院期间,患者接受了美托洛尔和达比加群治疗。出院时,患者在药物治疗下症状有部分改善,并计划在30天后返回门诊。我们的病例强调了对于出现全身性小脑共济失调、无意识或视觉改变的患者,应考虑双侧小脑上动脉供血区域因基底动脉顶端血栓形成导致缺血性卒中的重要性。临床试验编号:不适用。