Wang Ya, Pei Hualian, Guan Minfang, Sun Wenjing, Jia Yingying, Luo Junjun, Wang Hongxing
The First Affiliated Hospital of Ningbo University, Ningbo City, Zhejiang Province, PR China.
The Yangming Affiliated Hospital of Ningbo University, Yuyao City, Zhejiang Province, PR China.
Medicine (Baltimore). 2025 May 16;104(20):e42473. doi: 10.1097/MD.0000000000042473.
Patients with coronary heart disease may have a higher risk of medication discrepancy during hospital-family transition period because of the complexity of their diseases, the diversity of medicines brought out of hospital and the sensitivity of medicine taking time. This study aims to analyze the influencing factors of medication discrepancy in patients with coronary heart disease during hospital-family transition period. Patients admitted to the department of cardiovascular medicine from July 1, 2023 to June 30, 2024 in a hospital in Ningbo City, Zhejiang Province, China. Electronic medical record system and patients themselves before discharge collected the baseline data of patients with coronary heart disease. Within 2 weeks after discharge, the patients were investigated by telephone follow-up with the medication discrepancy tool. Logistic regression was used to determine the influencing factors of patients' medication discrepancy. The incidence of medication discrepancy in 107 patients within 2 weeks after discharge was 23.4%. The main discrepancy type is "medication omission." The causes of patient-induced medication discrepancy are relatively high, and the most common reason is "forgetting to take medicine." Logistic regression analysis showed that aspirin medication history and family APGAR index were the influencing factors of medication discrepancy. The incidence of medication discrepancy in patients with coronary heart disease in hospital-family transition period is high, among which omission is the most common. Aspirin medication history and family function are the key to identify patients' medication discrepancy. Medical staff should pay attention to the management of medication discrepancy in patients with coronary heart disease.
冠心病患者由于疾病的复杂性、出院带药的多样性以及服药时间的敏感性，在医院-家庭过渡期可能存在较高的用药差异风险。本研究旨在分析冠心病患者在医院-家庭过渡期用药差异的影响因素。选取中国浙江省宁波市某医院2023年7月1日至2024年6月30日心血管内科收治的患者。通过电子病历系统和患者出院前自身收集冠心病患者的基线数据。出院后2周内，采用用药差异工具对患者进行电话随访调查。采用Logistic回归分析确定患者用药差异的影响因素。107例患者出院后2周内用药差异发生率为23.4%。主要差异类型为“漏服药物”。患者导致用药差异的原因占比较高，最常见的原因是“忘记服药”。Logistic回归分析显示，阿司匹林用药史和家庭APGAR指数是用药差异的影响因素。冠心病患者在医院-家庭过渡期用药差异发生率较高，其中漏服最为常见。阿司匹林用药史和家庭功能是识别患者用药差异的关键。医务人员应重视冠心病患者用药差异的管理。
