Loire R, Berthou J D, Jean R, Gonin A
Arch Mal Coeur Vaiss. 1977 Feb;70(2):149-54.
A man of 54 had been treated over a 15 month period for pulmonary tuberculosis when aged 41, and had lived on the Ivory Coast and then in the Cameroons for 20 years. Eye signs were discovered in January 1971, and these, together with an eosinophilia, pointed to a possible filariasis which was later confirmed by immunofluorescence and the fixation of complement. Three months later, the patient developed congestive cardiac failure. On the 4th day of treatment with Notizine, multiple systemic emboli occurred, leading to death. Autopsy showed endomyocardial fibrosis with multiple ulceration of the left ventricle, the site of the emboli. The aetiology from filariasis and the mechanism of ulceration of the parietal endocarditis are discussed.
一名54岁男性在41岁时曾接受过为期15个月的肺结核治疗，他曾在象牙海岸和喀麦隆生活了20年。1971年1月发现眼部症状，这些症状连同嗜酸性粒细胞增多症提示可能患有丝虫病，后来通过免疫荧光和补体固定得到证实。三个月后，患者出现充血性心力衰竭。在用诺嗪治疗的第4天，发生了多发性全身栓塞，导致死亡。尸检显示心内膜纤维化，左心室有多处溃疡，此处为栓子形成部位。讨论了丝虫病的病因及心内膜炎壁层溃疡的机制。
