Topaz O, Edwards J E
Chest. 1985 Apr;87(4):476-82. doi: 10.1378/chest.87.4.476.
Pathologic investigation of 50 children, adolescents, and young adults who died suddenly and unexpectedly revealed that the most frequently encountered cardiovascular diseases were mitral valve prolapse (12 cases), myocarditis (12 cases), hypertrophic cardiomyopathy (six cases), and anomalous origin of a coronary artery from the aorta (two cases). Five subjects had no evidence of cardiac abnormalities. A striking family history of sudden death was encountered among eight subjects, of whom three had mitral valve prolapse and three had normal hearts. Assessing the circumstances surrounding sudden death, it was found that at the time of collapse, 32 subjects were engaged in regular activity, eight subjects were engaged in active athletics, and ten were found dead in bed. A relationship of the terminal event to emotional stress was reported in three subjects.
对50名突然意外死亡的儿童、青少年和年轻人进行的病理学调查显示，最常遇到的心血管疾病是二尖瓣脱垂（12例）、心肌炎（12例）、肥厚型心肌病（6例）以及冠状动脉起源于主动脉异常（2例）。5名受试者未发现心脏异常证据。8名受试者有明显的猝死家族史，其中3人有二尖瓣脱垂，3人心脏正常。评估猝死相关情况时发现，32名受试者在猝死时正在进行日常活动，8名受试者正在进行剧烈运动，10人被发现死于床上。3名受试者报告了终末事件与情绪压力之间的关系。
