Suppr超能文献

关节镜检查联合持续冲洗、单纯关节镜清创术和开放性关节切开术治疗原发性膝关节化脓性关节炎的比较。

A comparison of arthroscopy combined with continuous irrigation, arthroscopic debridement alone, and open arthrotomy for the treatment of septic arthritis of the native knee.

作者信息

Xiao Jie, Wu WenTing, Lin Shun, Zheng Yun, Lin KaiFeng, You Tao, Wu QiPing, Shen Feng, Yang Xiu, Han XueSong

机构信息

Fuzong Clinical Medical College of Fujian Medical University, Fuzhou, 350000, China.

Department of Orthopedics, The 900th Hospital of Joint Logistic Support Force, PLA, Fuzhou, 350025, China.

出版信息

BMC Musculoskelet Disord. 2025 May 19;26(1):494. doi: 10.1186/s12891-025-08724-7.

Abstract

BACKGROUND

The optimal surgical treatment for septic arthritis of the knee remains debatable, with few studies comparing different arthroscopic techniques. Furthermore, no study has simultaneously compared arthroscopy combined with continuous irrigation, arthroscopic debridement alone, and open arthrotomy. This study compared the efficacy and success rates of these three surgical methods and analyzed the risk factors for failure following initial surgery.

METHODS

Data were collected from patients who underwent surgery for native knee septic arthritis at the 900th Hospital of Joint Logistic Support Force in China between 2013 and 2023. A retrospective comparison of demographics, comorbidities, auxiliary examination results, causes, microorganisms, and efficacy outcomes was made among the three surgical groups.

RESULTS

A total of 65 patients (65 knees) were included in the study. All three groups had similar baseline characteristics. Postoperative C-reactive protein levels recovered faster in the continuous irrigation group than in the open group (p < 0.001). Both arthroscopic procedures showed a lower rate of hemoglobin decrease compared with open arthrotomy (p = 0.005 for the continuous irrigation group vs. open group; p = 0.023 for the debridement alone group vs. open group). The initial surgical success rate was higher in the continuous irrigation group (93.3%) than in the open group (65.2%) (p = 0.025). After adjusting for confounding factors through multivariate analysis, this advantage remained, with the risk of initial surgical failure in the open group being 11.31 times that in the continuous irrigation group (odds ratio = 11.31, 95% confidence interval: 1.7-75.24, p = 0.012). No significant differences were observed in postoperative range of motion, pain, or functional scores among the three groups.

CONCLUSION

No significant long-term functional differences were observed among the three surgical methods used to treat septic arthritis of the knee. The continuous irrigation group had an advantage in the early postoperative normalization of CRP levels and a higher initial surgical success rate than the open group.

CLINICAL TRIAL NUMBER

Not applicable.

摘要

背景

膝关节化脓性关节炎的最佳手术治疗方法仍存在争议,很少有研究比较不同的关节镜技术。此外,尚无研究同时比较关节镜联合持续冲洗、单纯关节镜清创术和切开手术。本研究比较了这三种手术方法的疗效和成功率,并分析了初次手术后失败的危险因素。

方法

收集2013年至2023年在中国人民解放军联勤保障部队第九〇〇医院接受原发性膝关节化脓性关节炎手术患者的数据。对三个手术组的人口统计学、合并症、辅助检查结果、病因、微生物和疗效结果进行回顾性比较。

结果

本研究共纳入65例患者(65膝)。三组的基线特征相似。持续冲洗组术后C反应蛋白水平恢复快于切开组(p<0.001)。与切开手术相比,两种关节镜手术的血红蛋白下降率均较低(持续冲洗组与切开组比较,p=0.005;单纯清创组与切开组比较,p=0.023)。持续冲洗组的初次手术成功率(93.3%)高于切开组((65.2%)(p=0.025)。通过多变量分析调整混杂因素后,这一优势仍然存在,切开组初次手术失败的风险是持续冲洗组的11.31倍(比值比=11.31,95%置信区间:1.7-75.24,p=0.012)。三组术后活动范围、疼痛或功能评分无显著差异。

结论

治疗膝关节化脓性关节炎的三种手术方法在长期功能上无显著差异。持续冲洗组在术后早期CRP水平正常化方面具有优势,且初次手术成功率高于切开组。

临床试验编号

不适用。

相似文献

4
Intracavity lavage and wound irrigation for prevention of surgical site infection.腔内灌洗和伤口冲洗预防手术部位感染
Cochrane Database Syst Rev. 2017 Oct 30;10(10):CD012234. doi: 10.1002/14651858.CD012234.pub2.
5
Guided tissue regeneration for periodontal infra-bony defects.牙周骨下袋缺损的引导组织再生术。
Cochrane Database Syst Rev. 2006 Apr 19(2):CD001724. doi: 10.1002/14651858.CD001724.pub2.
6
Sertindole for schizophrenia.用于治疗精神分裂症的舍吲哚。
Cochrane Database Syst Rev. 2005 Jul 20;2005(3):CD001715. doi: 10.1002/14651858.CD001715.pub2.
10
Saline irrigation for allergic rhinitis.用于变应性鼻炎的盐水冲洗
Cochrane Database Syst Rev. 2018 Jun 22;6(6):CD012597. doi: 10.1002/14651858.CD012597.pub2.

本文引用的文献

1
Native Joint Septic Arthritis.原发性关节化脓性关节炎
Antibiotics (Basel). 2024 Jun 27;13(7):596. doi: 10.3390/antibiotics13070596.
9
Post-operative septic arthritis after arthroscopy: modern diagnostic and therapeutic concepts.关节镜术后感染性关节炎:现代诊断与治疗理念。
Knee Surg Sports Traumatol Arthrosc. 2021 Oct;29(10):3149-3158. doi: 10.1007/s00167-021-06525-8. Epub 2021 Mar 23.

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验