Manterola Carlos, Biel Enrique, Rivadeneira Josue, Pera Manuel, Grande Luis
Center for Morphological and Surgical Studies, Universidad de La Frontera, Temuco, Chile.
PhD. Program in Medical Science, Universidad de La Frontera, Temuco, Chile.
World J Emerg Surg. 2025 May 19;20(1):41. doi: 10.1186/s13017-025-00617-3.
Acute gastric volvulus (AGV), is an uncommon complication of large paraesophageal hernias (PEH), resulting in closed-loop obstruction that may lead to incarceration and strangulation. The aim of this study was to summarize the evidence on clinical characteristics, surgical treatment, postoperative complications (POC), recurrence, and 30-day mortality (30DM), in patients undergoing surgery for AGV secondary to PEH.
A systematic review including studies on AGV secondary to PEH was conducted. Searches were performed in WoS, Embase, Medline, Scopus, BIREME-BV and SciELO. Primary outcomes included POC, 30DM and recurrence. Secondary outcomes comprised publication date, study origin and design, number of patients, volvulus type, hospital stay length, treatments; and methodological quality (MQ) of studies assessed using MInCir-T and MInCir-Pr scales. Descriptive statistics, weighted averages (WA), least squares logistic regression for comparisons, and meta-analysis of POC prevalence and HM were applied.
Of 1049 studies 171 met selection criteria, encompassing 15,178 patients. The WA age of patients was 75.3 ± 13.9 years, with 51.3% female. Most studies originated from USA (31.6%), with 52.6% published in the last decade. The WA of hospital stay was 7.9 ± 5.3 days. Among patients, 32.0% experienced POC, 7.6% required reinterventions and HM was 5.7%. MQ scores averaged 8.9 ± 2.3 (MInCir-T) and 13.4 ± 5.4 (MInCir-Pr). When comparing 1990-2014 and 2015-2024 periods, there were significant differences in age, reinterventions, readmissions and recurrence rates.
Despite surgical and resuscitative advancements, AGV prognosis remains poor, with high POC rates, prolonged hospitalization and significant 30DM. These findings emphasize the importance of early diagnosis and timely intervention for acute PEH to improve surgical outcomes.
急性胃扭转(AGV)是大型食管旁疝(PEH)的一种罕见并发症,可导致闭环梗阻,进而可能导致嵌顿和绞窄。本研究的目的是总结因PEH继发AGV而接受手术治疗的患者在临床特征、手术治疗、术后并发症(POC)、复发及30天死亡率(30DM)方面的证据。
对包括PEH继发AGV的研究进行系统综述。在Web of Science、Embase、Medline、Scopus、BIREME-BV和SciELO中进行检索。主要结局包括POC、30DM和复发。次要结局包括发表日期、研究来源和设计、患者数量、扭转类型、住院时间、治疗方法;以及使用MInCir-T和MInCir-Pr量表评估的研究方法学质量(MQ)。应用描述性统计、加权平均值(WA)、用于比较的最小二乘逻辑回归以及POC患病率和住院死亡率(HM)的荟萃分析。
在1049项研究中,171项符合入选标准,涵盖15178例患者。患者的加权平均年龄为75.3±13.9岁,女性占51.3%。大多数研究来自美国(31.6%),其中52.6%发表于过去十年。加权平均住院时间为7.9±5.3天。患者中,32.0%发生POC,7.6%需要再次干预,住院死亡率为5.7%。MQ评分平均为8.9±2.3(MInCir-T)和13.4±5.4(MInCir-Pr)。比较1990 - 2014年和2015 - 2024年这两个时期,在年龄、再次干预、再入院率和复发率方面存在显著差异。
尽管在手术和复苏方面取得了进展,但AGV的预后仍然很差,POC发生率高、住院时间延长且30DM显著。这些发现强调了对急性PEH进行早期诊断和及时干预以改善手术结局的重要性。