Pincus Theodore, Li Tengfei, Gibson Kathryn A
Rush University Medical Center, Chicago, Illinois.
Liverpool Hospital and Ingham Institute for Applied Medical Research, Liverpool, New South Wales, Australia, and University of New South Wales, Medicine and Health, Sydney, New South Wales, Australia.
ACR Open Rheumatol. 2025 May;7(5):e70025. doi: 10.1002/acr2.70025.
We analyzed 28 joint counts in 173 contemporary routine care patients with rheumatoid arthritis (RA), who had disease duration of 10 years and were examined in 2021, for swollen joint count (SJC), tender joint count (TJC)/pain on motion, and deformity joint count (DJC)/limited motion. In addition, we computed DJC according to Disease Activity Score in 28 joints (DA28), Clinical Disease Activity Index (CDAI), and Routine Assessment of Patient Index Data 3 (RAPID3) as remission/low or moderate/high activity or severity.
This report presents a retrospective analyses of a cross-sectional Australian database for medians and prevalences of SJC, TJC, and DJC, including in RA index categories.
Median values were 0 for SJC, 2.0 for TJC, and 4.0 for DJC, respectively, including SJC of 0,1 in 123 patients (71%), TJC of 0,1 in 82 patients (47%), SJC+TJC of 0,1 in 73 patients (42%), and DJC of 0,1 in 65 patients (38%). Among 4,498 joints, 1,330 with any abnormality included 286 swollen joints (6%), 590 tender joints (13%), 879 deformed joints (20%), 37 only swollen joints (1%), 289 only tender joints (6%), 659 only deformed joints (15%), 458 joints with two abnormalities (10%), and 80 joints with three abnormalities (2%). The 73 of all 173 with patients with SJC and TJC 0,1 (42%), included 56% to 67% who were classified in remission or low DAS28 ESR erythrocyte sedimentation rate, CDAI, or RAPID3 activity or severity, of whom 47% to 58% had DJC ≥2, whereas 11% to 36% were classified as moderate or high RA index activity or severity, of whom 57% to 58% had DJC ≥2.
SJC+TJC of 0,1 was more common than a DJC of 0,1 in contemporary patients with RA. DJC was ≥2 in the majority of patients who met SJC+TJC remission criteria for RA indices, as in patients who were classified as moderate/high although they met SJC+TJC remission criteria. DJC should be included in long-term routine care and RA databases.
我们分析了173例病程达10年且于2021年接受检查的当代类风湿关节炎（RA）常规护理患者的28个关节计数，以了解肿胀关节计数（SJC）、压痛关节计数（TJC）/活动时疼痛情况以及畸形关节计数（DJC）/活动受限情况。此外，我们根据28个关节疾病活动评分（DA28）、临床疾病活动指数（CDAI）和患者指数数据3常规评估（RAPID3）计算DJC，以确定缓解/低或中度/高活动度或严重程度。
本报告对一个澳大利亚横断面数据库进行回顾性分析，以获取SJC、TJC和DJC的中位数及患病率，包括RA指数类别中的数据。
SJC的中位数为0，TJC为2.0，DJC为4.0，其中123例患者（71%）的SJC为0或1，82例患者（47%）的TJC为0或1，73例患者（42%）的SJC + TJC为0或1，65例患者（38%）的DJC为0或1。在4498个关节中，1330个有任何异常，包括286个肿胀关节（6%）、590个压痛关节（13%）、879个畸形关节（20%）、37个仅肿胀关节（1%）、289个仅压痛关节（6%）、659个仅畸形关节（15%）、458个有两种异常的关节（10%）和80个有三种异常的关节（2%）。173例患者中SJC和TJC为0或1的73例（42%），包括56%至67%被分类为缓解或低DAS28（红细胞沉降率）、CDAI或RAPID3活动度或严重程度的患者，其中47%至58%的患者DJC≥2，而11%至36%被分类为中度或高度RA指数活动度或严重程度的患者，其中57%至58%的患者DJC≥2。
在当代RA患者中，SJC + TJC为0或1比DJC为0或1更常见。在符合RA指数SJC + TJC缓解标准的大多数患者中，DJC≥2，在符合SJC + TJC缓解标准但被分类为中度/高度的患者中也是如此。DJC应纳入长期常规护理和RA数据库。
