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亚洲慢性肾脏病继发性甲状旁腺功能亢进热消融专家共识声明

Asian consensus statement of experts on thermal ablation for secondary hyperparathyroidism in chronic kidney disease.

作者信息

Chai Huihui, Yue Wenwen, Sun Liping, Zhang Ling, Kim Ji-Hoon, Lin Wei-Che, Yu Jie, Yu Mingan, Wang Ningning, Wang Hong, Wang Shurong, Che Ying, Lu Qiang, Ren Jie, Liu Fangyi, Liu Yang, Xu Erjiao, Xu Hui, Xu Min, Zhu Jinge, Ruan Litao, Sun Xinping, Sun Desheng, Li Xiaolong, Li Changbin, Yang Meng, Wu Songsong, Yu Fei, Yu Songyuan, Yu Yongwu, Zhang Yifeng, Ouyang Chun, Zhang Bo, Zhang Xiaoliang, Zhang Lina, Luo Jun, Ji Zhengbiao, Zhou Jianqiao, Zhou Li, Zheng Yumin, Fang Lin, Zhao Qiyu, Zhao Binghui, Zhao Xinju, Hu Pengcheng, Rao Shengxiang, Jiang Hong, He Qingqing, Qian Linxue, Xu Dong, Huang Junyue, Cui Hongli, Jiang Tianan, Han Hong, Han Zhijiang, Cheng Jingning, Fan Youben, Baek Jung Hwan, Liang Ping, Xu Huixiong, Peng Chengzhong

机构信息

Department of Medical Ultrasound, Center of Minimally Invasive Treatment for Tumor, Shanghai Tenth People's Hospital, Ultrasound Research and Education Institute, Clinical Research Center for Interventional Medicine, School of Medicine, Tongji University, Shanghai, China (Chai, Yue, Sun, Zhu, Yu, Zhang, Peng).

Department of Nephrology, China-Japan Friendship Hospital, Beijing, China (Zhang).

出版信息

Int J Surg. 2025 Jul 1;111(7):4187-4210. doi: 10.1097/JS9.0000000000002510. Epub 2025 May 20.

DOI:10.1097/JS9.0000000000002510
PMID:40391972
Abstract

Secondary hyperparathyroidism (SHPT) is characterized by parathyroid hyperplasia, persistently elevated parathyroid hormone levels, and disturbances in mineral metabolism. Currently, a considerable amount of literature has consistently shown that thermal ablation is effective in maintaining parathyroid hormone levels within an appropriate range, normalizing calcium and phosphorus levels, improving clinical symptoms, and reducing the volume of parathyroid glands. However, there are currently no established guidelines regarding its utilization. The Asian consensus statement of experts on thermal ablation for SHPT in chronic kidney disease was jointly initiated by experts from China and Korea in the fields of nephrology, interventional ultrasound or radiology, thyroid surgery, ultrasound medicine, nuclear medicine, and diagnostic radiology-to formulate recommendations aimed at establishing standardized protocols for thermal ablation targeting the parathyroid glands. Based on the systematic review of literatures related to ultrasound-guided thermal ablation of parathyroid glands and the professional opinions of experts, the consensus statement covers the relevant content regarding thermal ablation treatment for SHPT, including indications, contraindications, pre-ablation evaluation, operational procedures, post-ablation follow-up, therapeutic effect evaluation, complications prevention and treatment. According to the Grading of Recommendations Assessment, Development and Evaluation, a total of 18 recommendations were given. This consensus statement will positively promote the standardization of ultrasound-guided thermal ablation of parathyroid glands.

摘要

继发性甲状旁腺功能亢进(SHPT)的特征是甲状旁腺增生、甲状旁腺激素水平持续升高以及矿物质代谢紊乱。目前,大量文献一致表明,热消融在将甲状旁腺激素水平维持在适当范围内、使钙和磷水平正常化、改善临床症状以及缩小甲状旁腺体积方面是有效的。然而,目前关于其应用尚无既定指南。慢性肾脏病SHPT热消融亚洲专家共识声明由中国和韩国在肾脏病学、介入超声或放射学、甲状腺外科、超声医学、核医学和诊断放射学领域的专家联合发起,旨在制定针对甲状旁腺热消融的标准化方案的建议。基于对甲状旁腺超声引导热消融相关文献的系统评价和专家的专业意见,该共识声明涵盖了SHPT热消融治疗的相关内容,包括适应证、禁忌证、消融前评估、操作程序、消融后随访、治疗效果评估、并发症防治。根据推荐分级的评估、制定和评价,共给出了18条建议。本共识声明将积极推动甲状旁腺超声引导热消融的规范化。

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