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肥胖管理药物作为代谢与减重手术的辅助手段:来自印度的共识推荐

Obesity Management Medications as Adjuncts to Metabolic and Bariatric Surgery: Consensus Recommendations from India.

作者信息

Goel Ramen, Dukkipati Nandakishore, Wadhawan Randeep, Katakwar Abhishek, Shah Shashank, Bhasker Aparna Govil, Nasta Amrit Manik, Goel Deep, Palaniappan Raj, Baig Sarfaraz, Khaitan Manish, Aggarwal Sandeep, Agrawal Abhay, Bawa Ashvind, Saurabh Gyan, Ahluwalia Jasmeet Singh, X L Jayanth Leo, Palep Jaydeep, Patil Kedar P, Kular Kuldeepak S, Narwaria Mahendra, Kaur Mandeep, Motwani Manish, Borude Rahul, Sinha Rakesh Kumar, Chaudhari Sadashiv, Pattanshetti Satish, Shah Sumeet, Ugale Surendra, John Suviraj James, Singhal Vikas

机构信息

Wockhardt Hospital, Mumbai Central, Mumbai, India.

KIMS Livlife, Hyderabad, India.

出版信息

Obes Surg. 2025 May 20. doi: 10.1007/s11695-025-07895-5.


DOI:10.1007/s11695-025-07895-5
PMID:40392474
Abstract

Obesity is a global health concern, with weight regain (WR) common after bariatric surgery. Clear guidelines on post-surgical medication use are essential. This expert consensus evaluates the role of obesity management medications (OMMs) in optimizing weight loss (WL) and preventing WR in individuals undergoing metabolic and bariatric surgery (MBS). Using a modified Delphi approach, a panel of 12 experts reviewed evidence and formulated consensus recommendations. Two voting rounds led to consensus on 11 of 15 statements, covering preoperative WL strategies and postoperative weight management. The recommendations guide OMM selection, timing, and effectiveness in enhancing WL outcomes. Integrating OMMs into bariatric care protocols can help clinicians improve long-term success rates in obesity management.

摘要

肥胖是一个全球性的健康问题,减肥手术后体重反弹(WR)很常见。关于术后药物使用的明确指南至关重要。本专家共识评估了肥胖管理药物(OMMs)在优化接受代谢和减肥手术(MBS)的个体的体重减轻(WL)和预防体重反弹方面的作用。通过采用改良的德尔菲法,一个由12名专家组成的小组审查了证据并制定了共识建议。两轮投票就15项陈述中的11项达成了共识,涵盖术前体重减轻策略和术后体重管理。这些建议指导了OMMs在提高体重减轻效果方面的选择、时机和有效性。将OMMs纳入减肥护理方案可以帮助临床医生提高肥胖管理的长期成功率。

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本文引用的文献

[1]
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Lancet Diabetes Endocrinol. 2025-3

[2]
A randomized, double-blind, placebo-controlled trial of weight loss using liraglutide 3.0 mg for weight recurrence after Roux-en-Y gastric bypass.

Surg Obes Relat Dis. 2025-2

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